(S)-β-Hydroxy-γ-butyrolactone
(S)-β-Hydroxy-γ-butyrolactone (CAS 7331-52-4) is a chiral organic compound with the molecular formula C4H6O3. This lactone serves as a valuable chiral building block in asymmetric synthesis. Its specific stereochemistry makes it a crucial intermediate for constructing complex molecules where precise spatial arrangement is required, particularly in pharmaceutical research and development.
- IUPAC
- (S)-4,5-Dihydro-4-hydroxy-2(3H)-furanone
- Synonyms
- (S)-4,5-Dihydro-4-hydroxy-2(3H)-furanone

Chiral Synthesis Intermediate
Utilised as a key chiral building block in the stereoselective synthesis of complex organic molecules, particularly pharmaceuticals and fine chemicals.
Asymmetric Synthesis
Essential reagent in asymmetric synthesis pathways, enabling the creation of enantiomerically pure compounds.
Lactone Chemistry Research
A fundamental lactone structure used in academic and industrial research for exploring novel synthetic methodologies.
| Molecular weight | 102.09 |
|---|---|
| Empirical formula | C4H6O3 |
| Assay | 96% |
| Boiling point | 98-100 °C/0.3 mmHg(lit.) |
| Density | 1.241 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.464(lit.) |
| Optical activity | [α]21/D −81°, c = 2 in ethanol |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 109 °C / 228.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-β-Hydroxy-γ-butyrolactone used for?
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(S)-β-Hydroxy-γ-butyrolactone is primarily used as a chiral building block in asymmetric synthesis, particularly for the creation of enantiomerically pure compounds in pharmaceutical research.
What is the CAS number and formula for (S)-β-Hydroxy-γ-butyrolactone?
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The CAS number is 7331-52-4 and the molecular formula is C4H6O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-β-Hydroxy-γ-butyrolactone with an assay of 96%. We do not represent this product as USP, BP, EP or other pharmacopoeia grades unless explicitly stated.
How should (S)-β-Hydroxy-γ-butyrolactone be handled?
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This compound is classified as a Warning with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, should be used. Handle in a well-ventilated area.
Is (S)-β-Hydroxy-γ-butyrolactone exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S)-β-Hydroxy-γ-butyrolactone.
How can I request a sample or quote for (S)-β-Hydroxy-γ-butyrolactone?
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Please contact our sales team directly through the website or by phone to request a sample or a quotation for (S)-β-Hydroxy-γ-butyrolactone.
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