Thyrotropin releasing hormone
Thyrotropin Releasing Hormone (TRH), CAS 24305-27-9, is a tripeptide with the molecular formula C16H22N6O4 and a molecular weight of 362.38 g/mol. Primarily known for its role in the hypothalamic-pituitary-thyroid axis, TRH acts as a releasing factor for thyrotropin. This compound is a valuable reagent in cell biology and neuroscience research, particularly for studies involving cell signaling and neuropeptide function.
- IUPAC
- L-Pyroglutamyl-L-histidyl-L-prolinamide,TRF,TRH,Thyroliberin,pGlu-His-Pro amide
- Synonyms
- L-Pyroglutamyl-L-histidyl-L-prolinamideTRFTRHThyroliberinpGlu-His-Pro amide

Cell Signaling Research
Thyrotropin Releasing Hormone is used to investigate intracellular signaling pathways mediated by the thyrotropin-releasing hormone receptor. It aids in understanding the cascade of events triggered upon receptor activation.
Neuroscience and Endocrinology Studies
As a key neuropeptide, TRH is instrumental in research exploring the hypothalamic-pituitary-thyroid axis and its influence on neurological functions and endocrine regulation. Its application aids in understanding hormone release mechanisms.
Peptide Synthesis and Analysis
This peptide serves as a standard or reference material in the synthesis and analytical validation of neuropeptides and related compounds. It is essential for researchers developing new peptide-based therapeutics or diagnostics.
| Molecular weight | 362.38 |
|---|---|
| Empirical formula | C16H22N6O4 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Thyrotropin Releasing Hormone used for?
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Thyrotropin Releasing Hormone (TRH) is used in cell biology and neuroscience research, particularly for studying cell signaling, the hypothalamic-pituitary-thyroid axis, and neuropeptide function. It acts as a releasing factor for thyrotropin.
What are the CAS number and formula for Thyrotropin Releasing Hormone?
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The CAS number for Thyrotropin Releasing Hormone is 24305-27-9, and its molecular formula is C16H22N6O4.
What grade and purity does Tech Serve Solutions supply for Thyrotropin Releasing Hormone?
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Tech Serve Solutions supplies Thyrotropin Releasing Hormone with a purity of ≥98% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Thyrotropin Releasing Hormone be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator filter (type N95 or P1). Store Thyrotropin Releasing Hormone at -20°C to maintain its integrity.
Is Thyrotropin Releasing Hormone a controlled substance?
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Based on the provided data, there is no indication that Thyrotropin Releasing Hormone (CAS 24305-27-9) is a controlled substance.
How is Thyrotropin Releasing Hormone packed, shipped, and exported?
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Thyrotropin Releasing Hormone is typically supplied as a powder and shipped according to its storage requirements (-20°C). Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote for Thyrotropin Releasing Hormone?
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To request a sample or a quote for Thyrotropin Releasing Hormone, please contact our sales team through the website or via direct inquiry, referencing the product name and CAS number 24305-27-9.
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