Tiagabine hydrochloride
Tiagabine hydrochloride (CAS 145821-59-6) is a chemical compound with a molecular weight of 375.55 (free base basis) and the empirical formula C20H25NO2S2 · xHCl. It is supplied as a white to tan powder. Tiagabine hydrochloride is primarily utilized in research settings, particularly for studying neurotransmission and its role in cellular processes, including investigations into serotoninergic transmission.
- IUPAC
- (-)-(R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]nipecotic acid hydrochloride,(3R)-1-[4,4-Bis(3-methyl-2-thienyl)-3-buten-1-yl]-3-piperidinecarboxylic acid hydrochloride
- Synonyms
- (-)-(R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]nipecotic acid hydrochloride,(3R)-1-[4,4-Bis(3-methyl-2-thienyl)-3-buten-1-yl]-3-piperidinecarboxylic acid hydrochloride
Neuroscience Research
Tiagabine hydrochloride serves as a valuable tool for researchers investigating the complexities of the central nervous system. It is employed to study neurotransmitter systems, such as serotoninergic transmission, and their impact on cellular function and signaling pathways.
GABAergic System Studies
As a modulator of GABA and glycine receptors, Tiagabine hydrochloride is used in studies focused on the GABAergic system. This research contributes to understanding inhibitory neurotransmission and its implications in neurological processes.
Cell Biology Investigations
The compound's bioactivity makes it useful in cell biology experiments exploring cellular responses to specific signaling molecules. Researchers can utilize Tiagabine hydrochloride to probe mechanisms related to ion channel function and cell signaling.
| Molecular weight | 375.55 (free base basis) |
|---|---|
| Empirical formula | C20H25NO2S2 · xHCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | H2O: ≥14 mg/mL |
| Optical activity | [α]/D -8.5 to 10°, c = 1 in H2O |
| Storage temperature | 2-8°C |
| Application | Tiagabine hydrochloride was used to study serotoninergic transmission in G1 cells.1 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tiagabine hydrochloride used for?
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Tiagabine hydrochloride is primarily used in research for studying neuroscience, cell biology, and the GABAergic system, including investigations into serotoninergic transmission.
What is the CAS number and formula for Tiagabine hydrochloride?
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The CAS number for Tiagabine hydrochloride is 145821-59-6. The empirical formula is C20H25NO2S2 · xHCl.
What grade and purity does Tech Serve Solutions supply for Tiagabine hydrochloride?
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Tech Serve Solutions supplies Tiagabine hydrochloride with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Tiagabine hydrochloride?
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Tiagabine hydrochloride is classified with a WGK Germany of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling and disposal information.
How is Tiagabine hydrochloride shipped and exported?
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Tech Serve Solutions, as a specialist global supplier, exports Tiagabine hydrochloride. Packaging and shipping adhere to all relevant regulations for hazardous materials, ensuring safe transport worldwide.
How can I request a sample or quote for Tiagabine hydrochloride?
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To request a sample or quote for Tiagabine hydrochloride, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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