GSK690693
GSK690693 (CAS: 937174-76-0; C21H27N7O3) is a potent and selective inhibitor of Protein Kinase B (Akt/PKB). With a molecular weight of 425.48 g/mol, this compound is valuable for researchers investigating cell signalling pathways, particularly in the context of cancer biology and neuroscience. It is supplied as a white to beige powder with an assay of ≥98% (HPLC).
- IUPAC
- 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol

Akt/PKB Pathway Research
GSK690693 serves as a crucial tool for studying the intricate roles of Akt/PKB in cellular processes such as cell survival, proliferation, and metabolism. Its selectivity enables precise investigation of this critical signalling node.
Cellular Signalling Studies
This compound is instrumental in dissecting complex cell signalling cascades. Researchers can utilise GSK690693 to understand the downstream effects of Akt inhibition in various cell types and biological models.
Neuroscience Research
Given its relevance to cell signaling, GSK690693 may be employed in neuroscience research to explore the involvement of the Akt pathway in neuronal function and potential neurological disorders.
Kinase/Phosphatase Biology
As a specific inhibitor of a key serine/threonine kinase, GSK690693 aids in clarifying the balance and interplay between kinase and phosphatase activities within cellular systems.
| Molecular weight | 425.48 |
|---|---|
| Empirical formula | C21H27N7O3 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble5 mg/mL (clear solution) |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GSK690693 used for?
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GSK690693 is primarily used as a research tool for investigating the Protein Kinase B (Akt/PKB) signalling pathway, cell survival, proliferation, and related cellular processes in cell biology, cancer research, and neuroscience.
What is the CAS number and molecular formula of GSK690693?
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The CAS number for GSK690693 is 937174-76-0, and its molecular formula is C21H27N7O3.
What grade and purity does Tech Serve Solutions supply for GSK690693?
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Tech Serve Solutions supplies GSK690693 with a purity of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should GSK690693 be handled and stored?
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GSK690693 is classified as toxic if swallowed (H301) and requires careful handling. Store at 2-8°C. Consult the Safety Data Sheet (SDS) for detailed safety precautions and emergency procedures. Ensure adequate ventilation and use appropriate personal protective equipment.
How is GSK690693 packed and shipped?
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GSK690693 is typically supplied as a white to beige powder. Shipments are managed in compliance with regulations for hazardous materials (UN 2811 6.1 / PGIII). TSS is experienced in global export of research chemicals.
How can I request a sample or quote for GSK690693?
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To request a sample or a quotation for GSK690693, please contact our sales team via the website or direct email, providing your research requirements and delivery details.
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