1-(Trifluoromethanesulfonyl)imidazole
1-(Trifluoromethanesulfonyl)imidazole (CAS: 29540-81-6, C4H3F3N2O2S) is a chemical compound with a molecular weight of 200.14 g/mol. It functions as a versatile building block in organic synthesis, particularly within heterocyclic chemistry. This reagent is characterised by its trifluoromethanesulfonyl group, enabling specific transformations in the creation of complex molecules. It is suitable for research and development purposes in the chemical and pharmaceutical industries.
- IUPAC
- 1-(Trifluoromethylsulfonyl)imidazole
Organic Synthesis Reagent
Utilised as a triflylating agent in organic synthesis for introducing the trifluoromethanesulfonyl group into various organic molecules. This is crucial for activating alcohols or amines for subsequent reactions.
Heterocyclic Chemistry
Serves as a valuable building block for the construction of complex heterocyclic compounds. Its imidazole core and reactive triflyl group facilitate diverse synthetic strategies.
Pharmaceutical Intermediate Synthesis
Employed in the multi-step synthesis of pharmaceutical intermediates. The incorporation of the trifluoromethylsulfonyl moiety can influence the pharmacokinetic properties of drug candidates.
| Molecular weight | 200.14 |
|---|---|
| Empirical formula | C4H3F3N2O2S |
| Assay | ≥95.0% (RT) |
| Density | 1.525 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.416 |
| Storage temperature | 2-8°C |
| Melting point | 19-21 °C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Trifluoromethanesulfonyl)imidazole used for?
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1-(Trifluoromethanesulfonyl)imidazole (CAS: 29540-81-6) is primarily used as a reagent in organic synthesis, particularly for triflylations and as a building block in heterocyclic chemistry and pharmaceutical intermediate synthesis.
What is the CAS number and chemical formula for 1-(Trifluoromethanesulfonyl)imidazole?
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The CAS number is 29540-81-6 and the chemical formula is C4H3F3N2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(Trifluoromethanesulfonyl)imidazole with an assay of ≥95.0% (RT). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 1-(Trifluoromethanesulfonyl)imidazole be handled?
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Handling requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a suitable respirator (e.g., multi-purpose combination respirator cartridge or type ABEK filter). It is harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332).
How is 1-(Trifluoromethanesulfonyl)imidazole shipped?
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1-(Trifluoromethanesulfonyl)imidazole is shipped as UN 2810, Class 6.1, Packing Group III, with relevant hazard statements and safety precautions for transport.
How can I request a sample or quote?
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To request a sample or quote for 1-(Trifluoromethanesulfonyl)imidazole, please contact our sales department through the website or provide your details via the online inquiry form.
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