1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester
Tech Serve Solutions proudly supplies 1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester (CAS: 903550-26-5), a heteroaryl boronate ester with the molecular formula C14H23BN2O3 and a molecular weight of 278.16 g/mol. This organometallic reagent is an essential building block in organic synthesis, particularly for cross-coupling reactions. It is crucial for the development of complex molecules within the pharmaceutical and agrochemical industries, offering reliable performance in sophisticated chemical transformations.
Suzuki-Miyaura Coupling Reagent
This boronate ester is extensively employed as a coupling partner in Suzuki-Miyaura reactions. It facilitates the formation of carbon-carbon bonds, enabling the synthesis of biaryl compounds and other complex organic structures vital for medicinal chemistry.
Pharmaceutical Intermediate Synthesis
Its specific heterocyclic structure and reactive boronic ester moiety make it a valuable intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). It aids in constructing intricate molecular frameworks with desired pharmacological properties.
Agrochemical Development
The compound serves as a key building block in the discovery and production of novel agrochemicals. Its application aids in designing molecules with improved efficacy and targeted action for crop protection.
Materials Science Research
Utilised in research settings for the development of advanced materials, where precise molecular architecture is required. Its ability to participate in C-C bond formation is instrumental in creating functional organic materials.
| Molecular weight | 278.16 |
|---|---|
| Empirical formula | C14H23BN2O3 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 74-78 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the construction of complex molecules in the pharmaceutical and agrochemical industries.
What is the CAS number and molecular formula?
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The CAS number is 903550-26-5 and the molecular formula is C14H23BN2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. It is suitable for research and technical applications. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should this chemical be handled and stored?
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Handle with appropriate personal protective equipment. Store at 2-8°C. This compound has a GHS classification of 3 for Water Hazard.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and reagents.
How can I request a sample or quote?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for this product.
How is 1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester synthesized?
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Published preparations of 1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester are documented in the chemical literature and patent records — see the synthesis and sourcing section on this page for reference links. Tech Serve Solutions supplies 1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester ready to use; request a quote for current grades and pack sizes.
How 1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester (903550-26-5) is synthesized — and where to buy it
This THP-protected pyrazole-5-boronic acid pinacol ester is a Suzuki–Miyaura cross-coupling building block: the tetrahydropyranyl group masks the pyrazole N–H during coupling and is removed afterwards under mild acid.
Published synthesis & references
Why make it?
Boronate esters and boronic acids degrade on storage, and an old lot quietly erodes coupling yield. We supply a fresh, assay-verified lot with a Certificate of Analysis.
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