SU 9516

CAS 377090-84-1C13H11N3O2Biochemicals & Reagents

SU 9516 (CAS 377090-84-1) is a chemical compound with the molecular formula C13H11N3O2 and a molecular weight of 241.25 g/mol. Supplied by Tech Serve Solutions as a brown crystalline solid, it functions as a selective inhibitor, particularly noted for its activity against Cyclin-Dependent Kinase 2 (CDK2). This compound is valuable in biochemical research for studying cell cycle regulation and related cellular processes.

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SU 9516 (C13H11N3O2) — chemical structure, CAS 377090-84-1; Life Science, fine chemical supplied by Tech Serve Solutions

A to CBioactive Small MoleculesBiochemicals and ReagentsCell BiologyCyclin Dependant Kinase 2Enzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitorsand Substrates

01 /Applications

Selective CDK2 Inhibition

SU 9516 is identified as a potent inhibitor of Cyclin-Dependent Kinase 2 (CDK2), with an IC50 value of 22 nM. It is utilized in research settings to investigate the role of CDK2 in cell cycle progression and other cellular functions.

Research in Cell Biology

As a bioactive small molecule, SU 9516 serves as a valuable tool in cell biology research. Its specific inhibitory action aids in dissecting signaling pathways involving CDKs and understanding their impact on cell proliferation and differentiation.

Biochemical Assays

The compound is suitable for use in biochemical assays to study kinase activity. Its high purity of ≥98% (HPLC) ensures reliable results when evaluating enzyme kinetics or screening for related compounds.

02 /Properties

Molecular weight	241.25
Empirical formula	C13H11N3O2
Assay	≥98% (HPLC)
Form	crystalline
Colour	brown
Solubility	DMSO: ~17 mg/mLH2O: insoluble
Application	Identified through a high-throughput screening with Cdk2. IC50=22 nM.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

377090-84-1

MDL number

MFCD05865243

05 /Additional specifications

Gene Information	human ... CDK2(1017), PDGFRB(5159), SRC(6714)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is SU 9516 used for?

SU 9516 is primarily used as a research tool to inhibit Cyclin-Dependent Kinase 2 (CDK2), aiding in the study of cell cycle regulation and related biological processes.

What is the CAS number and molecular formula for SU 9516?

The CAS number for SU 9516 is 377090-84-1, and its molecular formula is C13H11N3O2.

What grade and purity does Tech Serve Solutions supply for SU 9516?

Tech Serve Solutions supplies SU 9516 with a purity of ≥98% as determined by HPLC. This product is intended for research purposes and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety precautions when handling SU 9516?

When handling SU 9516, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. The compound is classified with a WGK Germany of 3.

How is SU 9516 typically packed and shipped?

SU 9516 is typically supplied in a brown crystalline form. Specific packaging details for export are available upon request, adhering to international shipping regulations for chemical substances.