SU 4312
SU 4312 (CAS 5812-07-7), with the molecular formula C17H16N2O and a molecular weight of 264.32, is a bioactive small molecule and enzyme inhibitor. It is identified as a tyrosine kinase inhibitor. SU 4312 has been utilised in research for studying developmental processes, specifically angiogenesis in zebrafish embryos, contributing to a deeper understanding of cellular signalling pathways.
- IUPAC
- 3-(4-Dimethylaminobenzylidenyl)-2-indolinone,3-[[(4-Dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one, E/Z mixture
- Synonyms
- 3-(4-Dimethylaminobenzylidenyl)-2-indolinone, 3-[[(4-Dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one, E/Z mixture
Angiogenesis Research
SU 4312 has been employed as a research tool to investigate the process of angiogenesis, particularly during the developmental stages of zebrafish embryos. This application aids in understanding the complex mechanisms regulating blood vessel formation.
Tyrosine Kinase Inhibition Studies
As a potent inhibitor of tyrosine kinases, SU 4312 is valuable for studying signalling pathways involving EGF receptor, PDGFR, and VEGFR. Its use helps elucidate the roles of these kinases in various cellular processes and disease states.
Cell Biology and Signaling Research
This compound serves as a reagent in cell biology and cell signalling research, enabling scientists to explore the intricate networks that control cell growth, differentiation, and survival. Its specific inhibitory action provides a tool for dissecting these pathways.
| Molecular weight | 264.32 |
|---|---|
| Empirical formula | C17H16N2O |
| Assay | ≥98% (HPLC) |
| Colour | orange |
| Solubility | DMSO: >10 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Application | SU 4312 was used to study angiogenesis during development of zebrafish embryos.2 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... FLT1(2321) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SU 4312 used for?
+
SU 4312 is used in research for studying angiogenesis, particularly in zebrafish embryos, and as a tyrosine kinase inhibitor to investigate signalling pathways involving EGF receptor, PDGFR, and VEGFR.
What is the CAS number and formula for SU 4312?
+
The CAS number for SU 4312 is 5812-07-7, and its molecular formula is C17H16N2O.
What grade and purity does Tech Serve Solutions supply for SU 4312?
+
Tech Serve Solutions supplies SU 4312 with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for SU 4312?
+
SU 4312 is classified with a GHS07 symbol and a Warning signal word. It is associated with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves, should be used when handling this chemical. Refer to the Safety Data Sheet (SDS) for comprehensive information.
How is SU 4312 shipped and exported?
+
SU 4312 is shipped and exported by Tech Serve Solutions in compliance with all relevant regulations for chemical transport. Storage at 2-8°C is recommended to maintain product integrity.
How can I request a sample or quote for SU 4312?
+
To request a sample or obtain a quote for SU 4312, please contact the Tech Serve Solutions sales team through our website or by phone.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis