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Substance P acetate salt hydrate

CAS 137348-11-9 (free base)C63H98N18O13S · xC2H4O2 · yH2OBiochemicals & Reagents

Substance P acetate salt hydrate (CAS: 137348-11-9) is a neuropeptide with the molecular formula C63H98N18O13S · xC2H4O2 · yH2O. As a key agonist in the tachykinin family, it plays a significant role in cell signaling, particularly within the nervous system. This compound is vital for research in areas such as cell biology, neuroscience, and obesity studies, serving as a critical tool for understanding neuropeptide function and GPCR modulation.

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Substance P acetate salt hydrate (C63H98N18O13S · xC2H4O2 · yH2O) — chemical structure, CAS 137348-11-9 (free base); Life Science, fine chemical supplied by Tech Serve Solutions
AgonistBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNeuropeptidesNeurotransmission (Obesity)Obesity ResearchPeptides and Proteins
01 /Applications

Neuroscience Research

Substance P is a well-characterised neuropeptide involved in pain transmission, neuroinflammation, and mood regulation. This acetate salt hydrate serves as a valuable reagent for in vitro and in vivo studies exploring neurological pathways and disorders.

Cell Signaling Studies

As an agonist for neurokinin receptors (NK1R), Substance P is used to investigate cellular responses mediated by G-protein coupled receptors (GPCRs). Its availability facilitates research into intracellular signaling cascades triggered by neuropeptide binding.

Obesity Research

Emerging research suggests a role for Substance P in regulating appetite and energy balance. This compound is employed in studies aiming to understand the neurochemical basis of obesity and potential therapeutic targets within neurotransmission pathways.

GPCR Modulation Research

This substance acts as a modulator for GPCRs, making it an essential tool for researchers studying receptor pharmacology and downstream effects. Its specific interaction with the NK1 receptor provides a focused model for GPCR research.

02 /Properties
Molecular weight1347.63 (anhydrous free base basis)
Empirical formulaC63H98N18O13S · xC2H4O2 · yH2O
Assay≥95% (HPLC)
Formpowder
Colourwhite
Solubility0.1 M acetic acid: soluble1 mg/mL
Storage temperature−20°C
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
PubChem substance
24899725
Beilstein registry
5153552
05 /Additional specifications
Mol Wtmol wt 1348 Da by calculation (Average Mass)
Gene Informationhuman ... TAC1(6863)
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Substance P acetate salt hydrate used for?

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Substance P acetate salt hydrate is used in scientific research, primarily as an agonist in neuroscience, cell biology, and obesity research. It helps study cell signaling, neuropeptide function, and neuroinflammation, particularly through its interaction with neurokinin-1 receptors (NK1R).

What are the CAS number and formula for Substance P acetate salt hydrate?

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The CAS number for the free base is 137348-11-9. The formula for the acetate salt hydrate is C63H98N18O13S · xC2H4O2 · yH2O.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Substance P acetate salt hydrate with a purity of ≥95% (HPLC). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, EP, or any other pharmacopoeial grade.

How should Substance P acetate salt hydrate be handled and stored?

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Handle Substance P acetate salt hydrate with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 respirator filter. Store the compound at -20°C. It is classified with WGK Germany 3, indicating a high hazard to water.

Is Substance P acetate salt hydrate a controlled substance?

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The provided data does not indicate that Substance P acetate salt hydrate is a controlled substance.

How is this chemical shipped and exported?

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As a global supplier established in 1998, Tech Serve Solutions has extensive experience in safely packing and exporting fine chemicals worldwide, adhering to all relevant international shipping regulations.

How can I request a sample or a quote for Substance P acetate salt hydrate?

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To request a sample or a quote for Substance P acetate salt hydrate, please contact our sales team through the website or by phone. We will be pleased to assist you with your research needs.

Need Substance P acetate salt hydrate in a specific grade or volume?