Streptozocin

CAS 18883-66-4C8H15N3O7Biochemicals & Reagents

Streptozocin (CAS 18883-66-4), a nitroso-urea compound with the molecular formula C8H15N3O7 and a molecular weight of 265.22, is primarily utilised as an antineoplastic and immunosuppressive antibiotic. It functions by inducing selective destruction of pancreatic beta cells. This specific action makes it a valuable research tool for inducing Type 1 diabetes in animal models for scientific study. Streptozocin is supplied as a white to light yellow powder.

IUPAC: N-(Methylnitrosocarbamoyl)-α-D-glucosamine,Streptozotocin

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Streptozocin (C8H15N3O7) — chemical structure, CAS 18883-66-4; Life Science, fine chemical supplied by Tech Serve Solutions

AntibioticsAntibiotics A to ZAntibiotics N-SAntibiotics by ApplicationApplication IndexBioactive Small MoleculesBiochemicals and ReagentsCell BiologyCell Signaling EnzymesEnzymes

01 /Applications

Induction of Type 1 Diabetes in Research Models

Streptozocin is employed in preclinical research to selectively destroy pancreatic beta cells, thereby inducing a state of Type 1 diabetes. This allows researchers to study the pathogenesis and progression of the disease and evaluate potential therapeutic interventions.

Antineoplastic Agent Research

As an antineoplastic antibiotic, Streptozocin has been investigated for its potential in cancer therapy, particularly against certain types of pancreatic islet cell tumours. Its cytotoxic properties are a subject of ongoing research.

Immunosuppressive Studies

The immunosuppressive nature of Streptozocin has led to its use in research settings to modulate immune responses. This can be relevant for studies investigating autoimmune diseases or the effects of immunosuppression on various biological processes.

02 /Properties

Molecular weight	265.22
Empirical formula	C8H15N3O7
Assay	≥75% α-anomer basis≥98% (HPLC)
Form	powder
Colour	white to light yellow
Storage temperature	−20°C
Application	Streptozocin is used to induce Type 1 diabetes for medical research.
Melting point	121 °C (dec.)(lit.)

03 /Safety & handling

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use
P308IF exposed or concerned

Protective equipment	Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3077 9 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	45
Safety statements (S)	53-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

18883-66-4

MDL number

MFCD00006607

PubChem substance

24899428

Beilstein registry

2060675

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Streptozocin used for?

Streptozocin (CAS 18883-66-4) is primarily used in research to induce Type 1 diabetes in animal models by selectively destroying pancreatic beta cells. It is also studied for its antineoplastic and immunosuppressive properties.

What are the CAS number and molecular formula for Streptozocin?

The CAS number for Streptozocin is 18883-66-4, and its molecular formula is C8H15N3O7.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Streptozocin with an assay of ≥75% on an α-anomer basis and ≥98% by HPLC. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.

How should Streptozocin be handled safely?

Streptozocin is classified with the GHS08 symbol and carries a 'Danger' signal word, with hazard statement H350 (May cause cancer). Appropriate personal protective equipment, including eyeshields, gloves, and specific respirator types (N100 or P3 filters), must be used. Handle only in a well-ventilated area or under a fume hood. Consult the Safety Data Sheet (SDS) for comprehensive handling instructions.

How is Streptozocin packaged and shipped?

Streptozocin is supplied as a white to light yellow powder and is stored at -20°C. It is shipped according to the UN 3077 classification (Environmentally hazardous substance, solid, n.o.s. Class 9, Packing Group III).

How can I request a sample or quote for Streptozocin?

To request a sample or obtain a quotation for Streptozocin, please contact our sales team through the website or by calling us directly. Provide your contact details and the quantity required.