Streptonigrin from Streptomyces flocculus
Streptonigrin from Streptomyces flocculus (CAS: 3930-19-6), with the empirical formula C25H22N4O8 and a molecular weight of 506.46 g/mol, is a potent antineoplastic antibiotic. It exhibits significant cytotoxic activity by interfering with DNA synthesis and function. Primarily utilised in biochemical research and as a tool for studying cellular mechanisms, Streptonigrin is essential for investigations into cancer biology and drug discovery.
- IUPAC
- Bruneomycin,Nigrin
- Synonyms
- BruneomycinNigrin

Antineoplastic Research
Streptonigrin serves as a critical agent in cancer research due to its cytotoxic properties and mechanism of action, which involves DNA damage. It is used to study tumour cell responses and evaluate potential therapeutic strategies.
Biochemical Studies
This compound is employed in biochemical research to investigate cellular processes, particularly DNA synthesis and repair mechanisms. Its unique properties make it valuable for understanding cellular stress responses and drug interactions.
Drug Discovery
As a bioactive molecule with antitumour activity, Streptonigrin can be a starting point or reference compound in the discovery and development of novel anti-cancer drugs.
| Molecular weight | 506.46 |
|---|---|
| Empirical formula | C25H22N4O8 |
| Assay | ≥98% |
| Storage temperature | 2-8°C |

Hazard statements
- H300Fatal if swallowed
Precautionary statements
- P264Wash thoroughly after handling
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3462 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 28 |
| Safety statements (S) | 53-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Streptonigrin used for?
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Streptonigrin is primarily used in research settings for antineoplastic studies, investigating its cytotoxic effects and mechanism of action, particularly its interference with DNA synthesis. It is also utilized in biochemical studies and drug discovery.
What are the CAS number and formula for Streptonigrin?
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The CAS number for Streptonigrin is 3930-19-6 and its empirical formula is C25H22N4O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Streptonigrin with an assay of ≥98%. We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should Streptonigrin be handled and stored?
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Streptonigrin is a Danger signal word substance (H300: Fatal if swallowed) requiring extreme caution. Store at 2-8°C. Always use appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a suitable respirator, and follow all safety instructions for handling toxic substances.
Is Streptonigrin packed and shipped internationally?
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Yes, Tech Serve Solutions exports and ships this chemical globally. Please refer to the provided UN 3462, 6.1 / PGI classification for shipping regulations.
How can I request a sample or quote for Streptonigrin?
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To request a sample or a quotation, please contact our sales team through the website or by phone, referencing the product name and CAS number.
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