Ethyl 4-amino-1-piperidinecarboxylate
Ethyl 4-amino-1-piperidinecarboxylate (CAS 58859-46-4; C8H16N2O2; MW 172.22) is a chemical building block primarily utilised in organic synthesis. This piperidine derivative serves as a key intermediate in the development of complex molecules, notably in the research of quinolin-2(1H)-one structures. Its specific reactivity makes it a valuable reagent for chemists engaged in pharmaceutical and materials science research, contributing to the creation of novel compounds. TSS supplies this chemical for laboratory and industrial applications.
- IUPAC
- 1-Carbethoxy-4-aminopiperidine

Synthesis of Quinolin-2(1H)-one Derivatives
Ethyl 4-amino-1-piperidinecarboxylate is a documented reagent in the synthesis pathway of quinolin-2(1H)-one derivatives. This application highlights its utility as a foundational component in constructing heterocyclic systems.
Pharmaceutical Intermediate
As a functionalised piperidine, this compound serves as a versatile building block in medicinal chemistry. It enables the introduction of the piperidine moiety into drug candidates, aiding in the exploration of new therapeutic agents.
Organic Synthesis Reagent
This chemical provides a valuable amino-piperidine scaffold for general organic synthesis. It is employed by researchers to create diverse molecular architectures and explore novel chemical transformations.
| Molecular weight | 172.22 |
|---|---|
| Empirical formula | C8H16N2O2 |
| Assay | 96% |
| Density | 1.004 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.483(lit.) |
| Application | Ethyl 4-amino-1-piperidinecarboxylate (1-Carbethoxy-4-aminopiperidine) was used in the synthesis of quinolin-2(1H)-one derivatives1. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 78 °C / 172.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 4-amino-1-piperidinecarboxylate used for?
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Ethyl 4-amino-1-piperidinecarboxylate is primarily used as a building block in organic synthesis, notably in the preparation of quinolin-2(1H)-one derivatives and as an intermediate in pharmaceutical research.
What is the CAS number and formula for Ethyl 4-amino-1-piperidinecarboxylate?
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The CAS number is 58859-46-4 and the empirical formula is C8H16N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 4-amino-1-piperidinecarboxylate with a minimum purity of 96%. This is a technical grade and not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations for handling Ethyl 4-amino-1-piperidinecarboxylate?
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This compound is classified as an irritant (H315, H319). Handle with appropriate personal protective equipment, including eyeshields and gloves, and use in a well-ventilated area. Ensure proper respiratory protection if needed, referencing the provided safety data.
Is Ethyl 4-amino-1-piperidinecarboxylate a controlled substance?
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The provided data does not indicate that Ethyl 4-amino-1-piperidinecarboxylate is a controlled substance.
How is Ethyl 4-amino-1-piperidinecarboxylate packed and shipped?
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Tech Serve Solutions exports chemicals globally. Specific packaging details and shipping information are available upon request, tailored to the quantity and destination.
How can I request a quote or sample?
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To request a quote or a sample of Ethyl 4-amino-1-piperidinecarboxylate, please contact our sales team through the website or by direct inquiry, providing your contact details and requirements.
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