Bis(4-nitrophenyl) carbonate
Bis(4-nitrophenyl) carbonate (CAS: 5070-13-3) is a chemical compound with the molecular formula (O2NC6H4O)2CO and a molecular weight of 304.21 g/mol. This reagent is primarily utilised in organic synthesis for the preparation of activated 4-nitrophenyl esters of N-protected amino acids. Its reliable performance makes it a valuable tool in peptide chemistry and other synthetic applications.
- IUPAC
- 4-Nitrophenyl carbonate
Preparation of Activated Esters
Bis(4-nitrophenyl) carbonate serves as a key reagent for synthesizing activated esters. It facilitates the conversion of N-protected amino acids into their corresponding 4-nitrophenyl esters, which are reactive intermediates.
Peptide Synthesis
In peptide chemistry, the activated esters derived from this compound are instrumental in forming peptide bonds. This application is crucial for the stepwise assembly of peptide chains in research and development.
Chemical Synthesis Reagent
Beyond peptide synthesis, Bis(4-nitrophenyl) carbonate acts as a versatile reagent in broader chemical synthesis. Its ability to introduce the 4-nitrophenyl ester moiety enables various esterification reactions.
| Molecular weight | 304.21 |
|---|---|
| Linear formula | (O2NC6H4O)2CO |
| Assay | ≥99% |
| Application | Reagent for the preparation of activated 4-nitrophenyl esters of N-protected amino acids. |
| Melting point | 136-139 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(4-nitrophenyl) carbonate used for?
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Bis(4-nitrophenyl) carbonate is used as a reagent for the preparation of activated 4-nitrophenyl esters of N-protected amino acids, particularly in peptide synthesis and other esterification reactions.
What is the CAS number and molecular formula for Bis(4-nitrophenyl) carbonate?
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The CAS number for Bis(4-nitrophenyl) carbonate is 5070-13-3, and its linear formula is (O2NC6H4O)2CO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis(4-nitrophenyl) carbonate with an assay of ≥99%. This product is intended for research and laboratory use, and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions for Bis(4-nitrophenyl) carbonate?
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Bis(4-nitrophenyl) carbonate is a warning-level chemical that may cause skin irritation (H315) and serious eye irritation (H319). Appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves, should be worn. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do, and continue rinsing (P305 + P351 + P338).
How is Bis(4-nitrophenyl) carbonate packaged and shipped?
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Tech Serve Solutions packages and exports Bis(4-nitrophenyl) carbonate according to international shipping regulations for chemical substances. Specific packaging details are available upon request.
How can I request a sample or quote for Bis(4-nitrophenyl) carbonate?
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To request a sample or a quote for Bis(4-nitrophenyl) carbonate, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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