(S)-(−)-Propylene oxide
(S)-(−)-Propylene oxide (CAS: 16088-62-3; C3H6O) is a chiral epoxide and a key organic building block. With a molecular weight of 58.08 g/mol, this optically active compound is instrumental in asymmetric synthesis. Its reactivity makes it a valuable intermediate for the production of enantiomerically pure compounds used in pharmaceuticals and fine chemicals. Tech Serve Solutions supplies this reagent for research and development purposes.
- IUPAC
- (S)-(−)-1,2-Epoxypropane,(S)-(−)-Methyloxirane

Asymmetric Synthesis
Utilised as a chiral building block for the stereoselective synthesis of complex molecules. Its epoxide ring can be opened enantioselectively to introduce chirality into target compounds, crucial for pharmaceutical intermediates.
Chemical Synthesis Intermediate
Serves as a versatile intermediate in organic synthesis. It enables the construction of various functionalised chiral molecules through reactions like nucleophilic ring-opening.
Epoxide Chemistry
As a reactive epoxide, it participates in ring-opening reactions with nucleophiles, leading to the formation of chiral alcohols and other functionalised organic compounds.
| Molecular weight | 58.08 |
|---|---|
| Empirical formula | C3H6O |
| Assay | 99% |
| Boiling point | 33-34 °C(lit.) |
| Density | 0.829 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.366(lit.) |
| Vapour pressure | 8.59 psi (20 °C) |
| Vapour density | 2 (vs air) |
| Autoignition temp | 1378 °F |



Hazard statements
- H224Extremely flammable liquid and vapour
- H302Harmful if swallowed
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -37 °C / -34.6 °F |
| Transport (UN / ADR) | UN 1280 3 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F+,T |
| Risk statements (R) | 45-12-20/21/22 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-Propylene oxide used for?
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(S)-(−)-Propylene oxide is primarily used in asymmetric synthesis and as a chemical synthesis intermediate for creating enantiomerically pure compounds, particularly in pharmaceutical research and development.
What is the CAS number and formula for (S)-(−)-Propylene oxide?
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The CAS number is 16088-62-3 and the molecular formula is C3H6O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-Propylene oxide with an assay of 99%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (S)-(−)-Propylene oxide be handled safely?
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(S)-(−)-Propylene oxide is highly flammable (H224) and harmful if swallowed, inhaled, or in contact with skin (H302 + H312 + H332). It is also suspected of causing cancer (H350). Handle with extreme care in a well-ventilated area, using appropriate personal protective equipment including eyeshields, gloves, and a full-face respirator.
Is (S)-(−)-Propylene oxide a controlled substance?
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The provided data does not indicate that (S)-(−)-Propylene oxide is a controlled substance. Please consult your local regulations for specific handling and reporting requirements.
How is (S)-(−)-Propylene oxide packed, shipped, and exported?
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Tech Serve Solutions can arrange for the packing, shipping, and export of (S)-(−)-Propylene oxide according to international regulations. Please contact us for specific logistical details and options.
How can I request a sample or quote for (S)-(−)-Propylene oxide?
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To request a sample or a quote for (S)-(−)-Propylene oxide, please use the contact form on our website or call our sales department directly.
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