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(S)-(−)-Propylene carbonate

CAS 51260-39-0C4H6O3Chemical Synthesis

(S)-(−)-Propylene carbonate (CAS: 51260-39-0, C4H6O3) is a chiral organic compound with a molecular weight of 102.09 g/mol. This optically active liquid, exhibiting an optical purity of 98% ee, serves as a valuable chiral building block in asymmetric synthesis and organic chemical manufacturing. Its defined specifications and chemical properties make it a reliable reagent for various synthetic applications.

IUPAC
(S)-1,2-Propanediol cyclic carbonate
Synonyms
(S)-1,2-Propanediol cyclic carbonate
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(S)-(−)-Propylene carbonate (C4H6O3) — chemical structure, CAS 51260-39-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisCarbonatesChemical SynthesisChiral Building BlocksOrganic Building Blocks
01 /Applications

Chiral Building Block

(S)-(−)-Propylene carbonate is utilised as a stereochemically defined precursor in the synthesis of complex chiral molecules. Its defined (S)-configuration allows for the precise introduction of chirality into target compounds.

Asymmetric Synthesis

This compound is employed in asymmetric synthesis strategies to create enantiomerically enriched products. It can participate in reactions that leverage its chiral centre to direct stereochemical outcomes.

Organic Synthesis Intermediate

As a cyclic carbonate, it functions as a versatile intermediate in various organic transformations. It can be opened or modified to yield functionalised propanediol derivatives.

02 /Properties
Molecular weight102.09
Empirical formulaC4H6O3
Assay98%
Boiling point240 °C(lit.)
Density1.189 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.422(lit.)
Optical activity[α]20/D −2°, neat
Optical purityee: 98% (GLC)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point113 °C / 235.4 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
51260-39-0
MDL number
MFCD00798264
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(−)-Propylene carbonate used for?

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(S)-(−)-Propylene carbonate is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in organic chemical manufacturing.

What is the CAS number and formula for (S)-(−)-Propylene carbonate?

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The CAS number is 51260-39-0 and the empirical formula (Hill notation) is C4H6O3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (S)-(−)-Propylene carbonate with an assay of 98%. This product is not represented as USP, BP, or EP grade.

What are the main safety hazards associated with (S)-(−)-Propylene carbonate?

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(S)-(−)-Propylene carbonate is a Warning substance (GHS07) and can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be used.

Is (S)-(−)-Propylene carbonate a controlled substance?

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The provided data does not indicate that (S)-(−)-Propylene carbonate is a controlled substance.

How is (S)-(−)-Propylene carbonate packed and shipped?

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Tech Serve Solutions, as a specialist global supplier and exporter of fine chemicals, ensures appropriate packaging and shipping procedures are followed for this compound.

How can I request a quote or sample for (S)-(−)-Propylene carbonate?

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Please contact Tech Serve Solutions directly through our website or sales channels to request a quote or sample for (S)-(−)-Propylene carbonate.

Need (S)-(−)-Propylene carbonate in a specific grade or volume?