(S)-(−)-Propylene carbonate
(S)-(−)-Propylene carbonate (CAS: 51260-39-0, C4H6O3) is a chiral organic compound with a molecular weight of 102.09 g/mol. This optically active liquid, exhibiting an optical purity of 98% ee, serves as a valuable chiral building block in asymmetric synthesis and organic chemical manufacturing. Its defined specifications and chemical properties make it a reliable reagent for various synthetic applications.
- IUPAC
- (S)-1,2-Propanediol cyclic carbonate
- Synonyms
- (S)-1,2-Propanediol cyclic carbonate

Chiral Building Block
(S)-(−)-Propylene carbonate is utilised as a stereochemically defined precursor in the synthesis of complex chiral molecules. Its defined (S)-configuration allows for the precise introduction of chirality into target compounds.
Asymmetric Synthesis
This compound is employed in asymmetric synthesis strategies to create enantiomerically enriched products. It can participate in reactions that leverage its chiral centre to direct stereochemical outcomes.
Organic Synthesis Intermediate
As a cyclic carbonate, it functions as a versatile intermediate in various organic transformations. It can be opened or modified to yield functionalised propanediol derivatives.
| Molecular weight | 102.09 |
|---|---|
| Empirical formula | C4H6O3 |
| Assay | 98% |
| Boiling point | 240 °C(lit.) |
| Density | 1.189 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.422(lit.) |
| Optical activity | [α]20/D −2°, neat |
| Optical purity | ee: 98% (GLC) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-Propylene carbonate used for?
+
(S)-(−)-Propylene carbonate is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in organic chemical manufacturing.
What is the CAS number and formula for (S)-(−)-Propylene carbonate?
+
The CAS number is 51260-39-0 and the empirical formula (Hill notation) is C4H6O3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (S)-(−)-Propylene carbonate with an assay of 98%. This product is not represented as USP, BP, or EP grade.
What are the main safety hazards associated with (S)-(−)-Propylene carbonate?
+
(S)-(−)-Propylene carbonate is a Warning substance (GHS07) and can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be used.
Is (S)-(−)-Propylene carbonate a controlled substance?
+
The provided data does not indicate that (S)-(−)-Propylene carbonate is a controlled substance.
How is (S)-(−)-Propylene carbonate packed and shipped?
+
Tech Serve Solutions, as a specialist global supplier and exporter of fine chemicals, ensures appropriate packaging and shipping procedures are followed for this compound.
How can I request a quote or sample for (S)-(−)-Propylene carbonate?
+
Please contact Tech Serve Solutions directly through our website or sales channels to request a quote or sample for (S)-(−)-Propylene carbonate.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis