(S)-(−)-Styrene oxide
(S)-(−)-Styrene oxide (CAS 20780-54-5, C8H8O) is a chiral epoxide and a valuable building block in organic synthesis. With a molecular weight of 120.15 g/mol, this compound is essential for introducing chirality into molecules. It is predominantly utilised in asymmetric synthesis and chemical transformations requiring enantiomerically pure intermediates, contributing to the development of complex organic compounds.
- IUPAC
- (S)-(−)-Phenyloxirane,(S)-Phenylethylene oxide
- Synonyms
- (S)-(−)-Phenyloxirane(S)-Phenylethylene oxide

Asymmetric Synthesis
Serves as a crucial chiral building block for enantioselective synthesis of complex organic molecules, including pharmaceuticals and fine chemicals. Its epoxide ring readily undergoes stereospecific ring-opening reactions.
Pharmaceutical Intermediates
Used in the synthesis of chiral drug candidates and active pharmaceutical ingredients (APIs). Its defined stereochemistry allows for precise control in the development of stereospecific therapeutics.
Organic Synthesis Reagent
A versatile reagent for creating new carbon-carbon and carbon-heteroatom bonds with controlled stereochemistry. Facilitates the construction of stereochemically rich compounds.
| Molecular weight | 120.15 |
|---|---|
| Empirical formula | C8H8O |
| Assay | 98% |
| Boiling point | 192-194 °C(lit.) |
| Density | 1.051 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.535(lit.) |
| Optical activity | [α]20/D −33°, neat |
| Optical purity | ee: 98% (HPLC) |
| Storage temperature | 2-8°C |


Hazard statements
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-20/21-36/38 |
| Safety statements (S) | 53-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-Styrene oxide used for?
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(S)-(−)-Styrene oxide is primarily used in asymmetric synthesis as a chiral building block for creating complex organic molecules, including pharmaceutical intermediates and fine chemicals.
What are the CAS number and formula for (S)-(−)-Styrene oxide?
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The CAS number for (S)-(−)-Styrene oxide is 20780-54-5, and its molecular formula is C8H8O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-Styrene oxide with an assay of 98% and 98% optical purity (ee). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product data.
How should (S)-(−)-Styrene oxide be handled safely?
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(S)-(−)-Styrene oxide is a dangerous substance. It is toxic if inhaled or in contact with skin, causes skin irritation and serious eye irritation, and may cause cancer. Always handle with appropriate personal protective equipment, including eyeshields, gloves, and a full-face respirator or appropriate filter, in a well-ventilated area. Refer to the safety data sheet for full handling instructions.
Is (S)-(−)-Styrene oxide a controlled substance?
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The provided data does not indicate that (S)-(−)-Styrene oxide is a controlled substance.
How is (S)-(−)-Styrene oxide packed and shipped?
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This product is shipped according to international regulations for hazardous materials (UN 2810, Class 6.1, PGIII). Specific packaging details can be provided upon request.
How can I request a quote or sample?
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To request a quote or sample of (S)-(−)-Styrene oxide, please contact our sales department through the website or by telephone.
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