(S)-(−)-Trifluorolactic acid
(S)-(−)-Trifluorolactic acid (CAS: 125995-00-8, Formula: CF3CH(OH)CO2H) is a chiral organic building block with a molecular weight of 144.05 g/mol. This trifluoromethylated alpha-hydroxy acid is valuable in asymmetric synthesis. Its unique structure allows for the introduction of trifluoromethyl groups and chirality into target molecules, making it a key intermediate in the development of pharmaceuticals and advanced materials.
- IUPAC
- (S)-(−)-3,3,3-Trifluoro-2-hydroxypropanoic acid
Chiral Building Block in Organic Synthesis
Utilised as a stereodefined synthon for constructing complex chiral molecules. It enables the introduction of a trifluoromethylated hydroxy acid moiety, crucial for modifying the properties of biologically active compounds.
Asymmetric Synthesis
Serves as a valuable chiral auxiliary or starting material in asymmetric synthesis. Its defined stereochemistry is exploited to control the formation of new chiral centres in organic transformations.
Pharmaceutical Intermediate Development
Employed in the synthesis pathways for novel pharmaceutical agents. The trifluoromethyl group can enhance metabolic stability and lipophilicity of drug candidates.
| Molecular weight | 144.05 |
|---|---|
| Linear formula | CF3CH(OH)CO2H |
| Assay | 98% |
| Optical activity | [α]20/D −42°, c = 1 in chloroform |
| Melting point | 72-76 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 1759 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-Trifluorolactic acid used for?
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(S)-(−)-Trifluorolactic acid is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals and advanced materials, owing to its trifluoromethylated hydroxy acid structure and defined stereochemistry.
What are the CAS number and chemical formula for (S)-(−)-Trifluorolactic acid?
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The CAS number for (S)-(−)-Trifluorolactic acid is 125995-00-8, and its chemical formula is CF3CH(OH)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-Trifluorolactic acid with an assay of 98%. This is a research or technical grade chemical, and TSS does not represent it as meeting USP, BP, EP, or other pharmacopoeial standards.
How should (S)-(−)-Trifluorolactic acid be handled safely?
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Handling requires appropriate personal protective equipment, including gloves, goggles, and a full-face respirator or appropriate cartridge filter, as it is classified as Danger with H314 (causes severe skin burns and eye damage). Ensure good ventilation and avoid contact with skin, eyes, and clothing.
Is (S)-(−)-Trifluorolactic acid controlled or scheduled?
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The provided safety data does not indicate that (S)-(−)-Trifluorolactic acid is a controlled or scheduled substance.
How is (S)-(−)-Trifluorolactic acid packed and exported?
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This chemical is typically packed according to relevant transport regulations (UN 1759, Class 8, PGIII). Tech Serve Solutions is experienced in global export and ensures compliant packaging and documentation.
How can I request a sample or quote for (S)-(−)-Trifluorolactic acid?
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To request a sample or a quotation, please contact our sales team via the website or direct email, providing your contact details and the quantity required.
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