1-(Trifluoromethyl)cyclobutanecarboxylic acid
1-(Trifluoromethyl)cyclobutanecarboxylic acid (CAS: 277756-45-3, Formula: C6H7F3O2, MW: 168.11) is a fluorinated organic building block. This carboxylic acid features a cyclobutane ring substituted with a trifluoromethyl group and a carboxyl group, making it a valuable intermediate in organic synthesis. It is typically supplied at 97% purity and is commonly used in chemical research and development for constructing complex molecules.
Fluorinated Organic Synthesis
Serves as a key intermediate for introducing the trifluoromethylcyclobutane moiety into more complex organic structures. Its unique structural features can influence the physicochemical properties of target molecules.
Medicinal Chemistry Research
The trifluoromethyl group is often incorporated to enhance metabolic stability and lipophilicity of drug candidates. This building block can be employed in the synthesis of novel pharmaceutical intermediates.
Materials Science
Can be utilised in the development of novel fluorinated materials. The presence of fluorine can impart unique properties such as thermal stability and altered surface characteristics.
| Molecular weight | 168.11 |
|---|---|
| Empirical formula | C6H7F3O2 |
| Assay | 97% |
| Density | 1.330 g/mL at 25 °C |
| Refractive index | n20/D 1.391 |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 96 °C / 204.8 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Trifluoromethyl)cyclobutanecarboxylic acid used for?
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1-(Trifluoromethyl)cyclobutanecarboxylic acid is primarily used as a building block in organic synthesis, particularly in medicinal chemistry research for creating novel fluorinated compounds and in materials science.
What are the CAS number and formula for 1-(Trifluoromethyl)cyclobutanecarboxylic acid?
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The CAS number is 277756-45-3 and the molecular formula is C6H7F3O2.
What grade and purity does Tech Serve Solutions supply for 1-(Trifluoromethyl)cyclobutanecarboxylic acid?
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Tech Serve Solutions supplies 1-(Trifluoromethyl)cyclobutanecarboxylic acid at an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-(Trifluoromethyl)cyclobutanecarboxylic acid be handled and stored?
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This compound is classified as Dangerous (Danger signal word) and is toxic if swallowed (H301) and causes serious eye irritation (H319). It requires appropriate personal protective equipment, including eyeshields, face shields, and gloves. Store at 2-8°C.
Is 1-(Trifluoromethyl)cyclobutanecarboxylic acid shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can export 1-(Trifluoromethyl)cyclobutanecarboxylic acid.
How can I request a quote or sample for 1-(Trifluoromethyl)cyclobutanecarboxylic acid?
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Please contact our sales team via the website or your dedicated account manager to request a quote or sample.
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