1-(Trifluoromethyl)cyclopropane-1-carboxylic acid
1-(Trifluoromethyl)cyclopropane-1-carboxylic acid (CAS: 277756-46-4; Formula: C5H5F3O2) is a unique organic compound with a molecular weight of 154.09 g/mol. Characterised by its trifluoromethyl group and cyclopropane ring, it functions as a valuable building block in organic synthesis. This carboxylic acid derivative is employed in the creation of complex molecules within the pharmaceutical and fine chemical industries, contributing to the development of novel compounds.

Organic Synthesis Intermediate
Serves as a key building block for constructing intricate molecular architectures. Its trifluoromethyl and cyclopropane moieties offer unique reactivity and structural properties for advanced chemical synthesis.
Pharmaceutical Research
Utilised in the development of new pharmaceutical agents. The incorporation of the trifluoromethyl group can influence a drug candidate's metabolic stability, lipophilicity, and binding affinity.
Fine Chemical Manufacturing
A versatile reagent in the fine chemical sector for producing specialised compounds. It aids in the synthesis of materials with specific electronic or physical properties.
| Molecular weight | 154.09 |
|---|---|
| Empirical formula | C5H5F3O2 |
| Assay | 97% |
| Melting point | 86-90 °C |


Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Trifluoromethyl)cyclopropane-1-carboxylic acid primarily used for?
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1-(Trifluoromethyl)cyclopropane-1-carboxylic acid is primarily used as a building block in organic synthesis, particularly in the pharmaceutical and fine chemical industries for the development of novel compounds.
What is the CAS number and molecular formula for this compound?
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The CAS number is 277756-46-4, and the molecular formula is C5H5F3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(Trifluoromethyl)cyclopropane-1-carboxylic acid with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 1-(Trifluoromethyl)cyclopropane-1-carboxylic acid be handled safely?
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This compound is classified as Danger with hazards H301 (Toxic if swallowed) and H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (e.g., N100 or P3 filters), is essential. Handle in a well-ventilated area.
Is this compound available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and we can arrange for the export of 1-(Trifluoromethyl)cyclopropane-1-carboxylic acid.
How can I request a quote or sample?
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To request a quote or sample of 1-(Trifluoromethyl)cyclopropane-1-carboxylic acid, please contact our sales team through our website or by phone.
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