Chlorophenylsilane

CAS 4206-75-1C6H5SiH2ClChemical Synthesis

Chlorophenylsilane (CAS: 4206-75-1, Formula: C6H5SiH2Cl) is a reactive organosilicon compound with a molecular weight of 142.66 g/mol. This colourless liquid serves as a valuable building block in organic synthesis and as a reagent for introducing silicon-based functional groups. It is primarily utilised in chemical synthesis and as a protecting or derivatizing agent in various research and development applications.

Email us

Chlorophenylsilane (C6H5SiH2Cl) — chemical structure, CAS 4206-75-1; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisSilicon-BasedSynthetic Reagents

01 /Applications

Chemical Synthesis Intermediate

Chlorophenylsilane acts as a versatile intermediate in the synthesis of more complex organosilicon compounds. Its reactive Si-Cl bond allows for nucleophilic substitution reactions, enabling the formation of new carbon-silicon or other silicon-heteroatom bonds.

Protecting Group Chemistry

In organic synthesis, Chlorophenylsilane can be employed to protect hydroxyl or amine functionalities. The resulting silyl ethers or silyl amines are stable under various reaction conditions and can be selectively removed later in the synthetic sequence.

Derivatization Reagent

This compound can be used to derivatize molecules for analytical purposes, such as gas chromatography. The introduction of a silyl group can improve volatility and thermal stability of analytes.

Research and Development

Chlorophenylsilane is a useful reagent in academic and industrial research labs exploring novel silicon-containing materials or reaction pathways. Its specific reactivity profile makes it suitable for targeted synthetic transformations.

02 /Properties

Molecular weight	142.66
Linear formula	C6H5SiH2Cl
Assay	97%
Boiling point	41 °C/9 mmHg(lit.)
Density	1.070 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.5260(lit.)

03 /Safety & handling

GHS hazard pictogram: Flammable (GHS02) — Flammable

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H226Flammable liquid and vapour
H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	54 °C / 129.2 °F
Transport (UN / ADR)	UN 2920 3(8) / PGII
Water hazard class (WGK, DE)	1
Hazard codes (EU)	C
Risk statements (R)	10-34
Safety statements (S)	16-26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

4206-75-1

MDL number

MFCD03701605

PubChem substance

24880486

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Chlorophenylsilane used for?

Chlorophenylsilane is primarily used in chemical synthesis as an intermediate, and as a reagent for protecting or derivatizing other molecules, particularly in research and development settings.

What are the CAS number and formula for Chlorophenylsilane?

The CAS number for Chlorophenylsilane is 4206-75-1, and its chemical formula is C6H5SiH2Cl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Chlorophenylsilane with a minimum assay of 97%. This product is intended for research and technical use and is not represented as USP, BP, EP, or pharmaceutical grade.

How should Chlorophenylsilane be handled safely?

Chlorophenylsilane is a flammable liquid and causes severe skin burns and eye damage. Handle with extreme care in a well-ventilated area, wearing appropriate personal protective equipment including gloves, goggles, face shield, and respiratory protection. Refer to the Safety Data Sheet for detailed handling procedures.

Is Chlorophenylsilane shipped internationally?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Chlorophenylsilane, and can arrange for international shipment according to regulations.

How can I request a quote or sample of Chlorophenylsilane?

To request a quote or a sample of Chlorophenylsilane, please contact our sales department via the website or provide your details through the product inquiry form.