Chlorotribenzylsilane

CAS 18740-59-5(C6H5CH2)3SiClChemical Synthesis

Chlorotribenzylsilane (CAS: 18740-59-5) is a silicon-based chemical reagent with the linear formula (C 6 H 5 CH 2 ) 3 SiCl. This compound has a molecular weight of 336.93 g/mol. It is primarily utilised in chemical synthesis as a protecting agent for hydroxyl groups, enabling selective reactions in complex organic molecules. Its utility lies in its ability to introduce a robust, yet cleavable, tribenzylsilyl protecting group.

IUPAC: Tribenzylchlorosilane,Tribenzylsilyl chloride
Synonyms: TribenzylchlorosilaneTribenzylsilyl chloride

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Chlorotribenzylsilane ((C6H5CH2)3SiCl) — chemical structure, CAS 18740-59-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisSilicon-BasedSynthetic Reagents

01 /Applications

Hydroxyl Group Protection

Chlorotribenzylsilane serves as an effective reagent for the protection of hydroxyl (-OH) groups in organic synthesis. The tribenzylsilyl ether formed is stable under various reaction conditions, facilitating subsequent chemical transformations on other parts of the molecule.

Organic Synthesis Reagent

As a versatile synthetic reagent, it finds application in multi-step synthesis pathways where precise control over functional group reactivity is required. Its silicon-based structure offers unique properties for derivatization and protection strategies.

Protecting Group Chemistry

This compound is valuable in protecting and derivatizing reagents, specifically for its role in introducing the tribenzylsilyl moiety. This protection strategy is particularly useful in the synthesis of complex molecules like pharmaceuticals and natural products.

02 /Properties

Molecular weight	336.93
Linear formula	(C6H5CH2)3SiCl
Assay	97%
Application	Reagent for OH protection.
Melting point	139-142 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3261 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

18740-59-5

MDL number

MFCD00004768

Beilstein registry

2942947

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Chlorotribenzylsilane used for?

Chlorotribenzylsilane is used as a reagent for protecting hydroxyl groups in organic synthesis, forming stable tribenzylsilyl ethers.

What is the CAS number and formula for Chlorotribenzylsilane?

The CAS number for Chlorotribenzylsilane is 18740-59-5 and its linear formula is (C 6 H 5 CH 2 ) 3 SiCl.

What grade and purity does Tech Serve Solutions supply for Chlorotribenzylsilane?

Tech Serve Solutions supplies Chlorotribenzylsilane with an assay of 97%. This is a technical grade for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.

What are the safety and handling precautions for Chlorotribenzylsilane?

Chlorotribenzylsilane is classified as Danger (GHS05) with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, is essential. It must be handled with extreme care to avoid contact and inhalation.

How is Chlorotribenzylsilane packed, shipped, and exported?

As a globally recognised supplier since 1998, Tech Serve Solutions adheres to stringent international regulations for the packing, shipping, and export of chemicals like Chlorotribenzylsilane, ensuring safe and compliant transit.

How can I request a sample or quote for Chlorotribenzylsilane?

To request a sample or a quote for Chlorotribenzylsilane, please contact our sales team through the website or by calling our office, providing your specific requirements.