Chlorotriethylsilane
Chlorotriethylsilane (CAS: 994-30-9) is an organosilicon compound with the linear formula (C2H5)3SiCl and a molecular weight of 150.72 g/mol. This flammable liquid is primarily utilised as a derivatization reagent in gas chromatography (GC) and in various chemical synthesis applications. Its ability to introduce a triethylsilyl group makes it valuable for protecting functional groups and enhancing the volatility of analytes for chromatographic analysis.
- IUPAC
- Silane E3,TESCl,Triethylchlorosilane
- Synonyms
- TriethylchlorosilaneTESClChlorotriethyl-silaneSilane, chlorotriethyl-

Gas Chromatography Derivatization
Chlorotriethylsilane is employed as a silylation reagent to derivatize compounds for gas chromatography analysis. It reacts with active hydrogen atoms to form more volatile and thermally stable derivatives, improving chromatographic separation and detection.
Chemical Synthesis
This compound serves as a versatile building block in organic synthesis. It is used to introduce the triethylsilyl protecting group onto alcohols, amines, and other functionalities, facilitating subsequent reactions.
Analytical Reagent
As an analytical reagent, Chlorotriethylsilane is useful in preparing samples for various analytical techniques. Its application in derivatization enhances the detectability and quantitation of target analytes.
| Molecular weight | 150.72 |
|---|---|
| Linear formula | (C2H5)3SiCl |
| Assay | ≥99.0% |
| Grade | for GC derivatization |
| Boiling point | 142-144 °C(lit.) |
| Density | 0.898 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.43(lit.) |
| Concentration | 1.0 M in THF |



Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 30 °C / 86 °F |
| Transport (UN / ADR) | UN 2986 3(8) / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-14-22-35 |
| Safety statements (S) | 16-26-36/37/39-43-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorotriethylsilane used for?
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Chlorotriethylsilane is primarily used as a derivatization reagent for gas chromatography and in chemical synthesis as a silylating agent to protect functional groups.
What are the CAS number and formula for Chlorotriethylsilane?
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The CAS number is 994-30-9 and the linear formula is (C2H5)3SiCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlorotriethylsilane with an assay of ≥99.0% and a grade specified for GC derivatization.
How should Chlorotriethylsilane be handled safely?
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Chlorotriethylsilane is a Danger hazard class, flammable, corrosive, and toxic if swallowed. It reacts violently with water. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for detailed guidance.
How is Chlorotriethylsilane packed, shipped, and exported?
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Products are packed according to international shipping regulations for hazardous materials and exported globally by Tech Serve Solutions.
How can I request a quote or sample for Chlorotriethylsilane?
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Please contact our sales team via the website to request a quote or a sample for Chlorotriethylsilane.
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