Chlorotriisobutylsilane
Chlorotriisobutylsilane (CAS: 13154-25-1) is a silicon-based organosilicon compound with the linear formula [(CH₃)₂CHCH₂]₃SiCl. With a molecular weight of 234.88 g/mol, it functions as a versatile reagent in organic synthesis. Its primary utility lies in the protection and derivatization of functional groups, particularly alcohols, owing to the steric bulk of the triisobutylsilyl moiety.
- IUPAC
- Triisobutylchlorosilane,Triisobutylsilyl chloride
- Synonyms
- TriisobutylchlorosilaneTriisobutylsilyl chloride
![Chlorotriisobutylsilane ([(CH3)2CHCH2]3SiCl) — chemical structure, CAS 13154-25-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F13154-25-1.png&w=3840&q=75)
Protecting Group Reagent
Triisobutylsilyl chloride is employed to protect hydroxyl groups in complex organic molecules. The bulky isobutyl substituents provide steric hindrance, enhancing stability against certain reaction conditions compared to less hindered silyl ethers.
Derivatization Agent
This compound serves as a derivatization agent to modify the properties of molecules, often to improve their volatility or detectability in analytical techniques like gas chromatography (GC).
Organic Synthesis
As a silicon-based reagent, Chlorotriisobutylsilane is valuable in various synthetic transformations where the introduction of a sterically demanding silyl group is required to direct regioselectivity or control reactivity.
| Molecular weight | 234.88 |
|---|---|
| Linear formula | [(CH3)2CHCH2]3SiCl |
| Assay | 99% |
| Density | 0.875 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.448(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 87 °C / 188.6 °F |
| Transport (UN / ADR) | UN 2987 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorotriisobutylsilane used for?
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Chlorotriisobutylsilane is primarily used as a protecting group reagent for alcohols and as a derivatizing agent in organic synthesis. Its bulky triisobutylsilyl moiety offers steric protection.
What is the CAS number and formula for Chlorotriisobutylsilane?
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The CAS number for Chlorotriisobutylsilane is 13154-25-1, and its linear formula is [(CH₃)₂CHCH₂]₃SiCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlorotriisobutylsilane with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should Chlorotriisobutylsilane be handled safely?
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Chlorotriisobutylsilane is a corrosive substance (GHS05, Danger, H314) that causes severe skin burns and eye damage. Appropriate personal protective equipment, including full-face respirators, gloves, and goggles, must be worn. Handle in a well-ventilated area and follow emergency procedures.
Is Chlorotriisobutylsilane controlled or scheduled?
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The provided data does not indicate that Chlorotriisobutylsilane is a controlled or scheduled substance.
How is Chlorotriisobutylsilane packed, shipped, and exported?
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Chlorotriisobutylsilane is shipped as UN 2987, Hazard Class 8, Packing Group II. Tech Serve Solutions adheres to all international shipping regulations for hazardous materials.
How can I request a sample or quote for Chlorotriisobutylsilane?
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To request a sample or a quote, please contact our sales team directly through our website or by phone. Please reference the product name and CAS number.
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