2-Amino-4,5-dimethoxybenzoic acid
2-Amino-4,5-dimethoxybenzoic acid (CAS 5653-40-7) is an aromatic amino acid derivative with the molecular formula H₂NC₆H₂(OCH₃)₂CO₂H and a molecular weight of 197.19 g/mol. It serves as a valuable building block in chemical synthesis, particularly within the fields of chemical biology and peptide chemistry. This compound is frequently employed in the creation of unnatural amino acid derivatives and other complex organic molecules.
- IUPAC
- 4,5-Dimethoxyanthranilic acid,6-Aminoveratric acid
- Synonyms
- H2NC6H2(OCH3)2CO2H4,5-Dimethoxyanthranilic acid6-Aminoveratric acid

Chemical Synthesis Intermediate
This compound acts as a key intermediate in multi-step organic syntheses. Its functional groups allow for diverse chemical transformations, facilitating the construction of more complex molecular architectures.
Peptide Chemistry
It is utilised in peptide chemistry for the incorporation of modified amino acid residues into peptide chains. This allows for the exploration of novel peptide structures and functionalities.
Unnatural Amino Acid Derivative Synthesis
2-Amino-4,5-dimethoxybenzoic acid is instrumental in the synthesis of unnatural amino acids. These modified amino acids are crucial for research in areas such as drug discovery and protein engineering.
Chemical Biology Research
The compound finds application in chemical biology for developing molecular probes or modifying biological systems. Its structure can be tailored for specific interactions within biological pathways.
| Molecular weight | 197.19 |
|---|---|
| Linear formula | H2NC6H2(OCH3)2CO2H |
| Assay | ≥97.0% (T) |
| Melting point | 169-173 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-4,5-dimethoxybenzoic acid used for?
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2-Amino-4,5-dimethoxybenzoic acid is primarily used as an intermediate in chemical synthesis, particularly for creating unnatural amino acid derivatives, and in peptide and chemical biology research.
What is the CAS number and molecular formula?
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The CAS number for 2-Amino-4,5-dimethoxybenzoic acid is 5653-40-7. Its linear molecular formula is H₂NC₆H₂(OCH₃)₂CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-4,5-dimethoxybenzoic acid with an assay of ≥97.0% (T). We do not represent this product as USP, EP, or BP grade.
How should 2-Amino-4,5-dimethoxybenzoic acid be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Ensure adequate ventilation, and avoid breathing dust. Refer to the safety data sheet for comprehensive handling information.
How is this chemical exported or shipped?
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Tech Serve Solutions exports fine chemicals globally. Packaging and shipping are handled in compliance with international regulations for chemical transport.
How can I request a quote or sample?
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To request a quote or sample of 2-Amino-4,5-dimethoxybenzoic acid, please contact our sales team through the website or via direct inquiry, providing your contact details and the quantity required.
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