Chlorotributylsilane
Chlorotributylsilane (CAS 995-45-9) is a silicon-based organochlorine compound with the linear formula [CH3(CH2)3]3SiCl and a molecular weight of 234.88 g/mol. As a versatile synthetic reagent, it is primarily employed in chemical synthesis, particularly for protection and derivatization reactions. Its utility extends to being a key intermediate in the preparation of various organosilicon compounds, making it valuable in research and development settings.
- IUPAC
- Chlorotributylsilane,Tributylchlorosilane,Tributylsilyl chloride
- Synonyms
- TributylchlorosilaneTributylsilyl chloride
![Chlorotributylsilane ([CH3(CH2)3]3SiCl) — chemical structure, CAS 995-45-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F995-45-9.png&w=3840&q=75)
Protecting Group Reagent
Chlorotributylsilane is utilised as a reagent to introduce the tributylsilyl (TBS) protecting group onto alcohols and other nucleophilic functional groups. This temporary modification facilitates selective reactions elsewhere in a molecule by preventing unwanted reactions at the protected site.
Derivatization Agent
In analytical chemistry, chlorotributylsilane can be used to derivatize compounds, enhancing their volatility or detectability in techniques such as gas chromatography (GC). This aids in the identification and quantification of specific analytes.
Intermediate in Organic Synthesis
The compound serves as a precursor in the synthesis of more complex organosilicon molecules. Its reactive silicon-chlorine bond allows for nucleophilic substitution reactions, enabling the formation of new carbon-silicon bonds.
| Molecular weight | 234.88 |
|---|---|
| Linear formula | [CH3(CH2)3]3SiCl |
| Assay | 97% |
| Boiling point | 250-252 °C(lit.) |
| Density | 0.879 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.446(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 97 °C / 206.6 °F |
| Transport (UN / ADR) | UN 2987 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorotributylsilane used for?
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Chlorotributylsilane is used in chemical synthesis as a protecting and derivatizing reagent, particularly for introducing the tributylsilyl group and in the synthesis of organosilicon compounds.
What is the CAS number and formula for Chlorotributylsilane?
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The CAS number for Chlorotributylsilane is 995-45-9, and its linear formula is [CH3(CH2)3]3SiCl.
What grade and purity does Tech Serve Solutions supply for Chlorotributylsilane?
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Tech Serve Solutions supplies Chlorotributylsilane with a minimum assay of 97%. This product is supplied for laboratory and manufacturing use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should Chlorotributylsilane be handled safely?
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Chlorotributylsilane is a corrosive substance. Handle with appropriate personal protective equipment, including gloves, goggles, and a face shield or full-face respirator. Ensure adequate ventilation and refer to the Safety Data Sheet for detailed handling and emergency procedures. It carries hazard statement H314 (Causes severe skin burns and eye damage).
Is Chlorotributylsilane available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Chlorotributylsilane. Please contact our sales team for international shipping details.
How can I request a sample or quote for Chlorotributylsilane?
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To request a sample or a quotation for Chlorotributylsilane, please contact our customer service department through the website or by phone, providing your contact details and the quantity required.
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