Chlorosulfonyl isocyanate
Chlorosulfonyl isocyanate (CAS 1189-71-5), molecular formula ClSO2NCO, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- N-Carbonylsulfamyl chloride,CSI

| Molecular weight | 141.53 |
|---|---|
| Linear formula | ClSO2NCO |
| Assay | 98% |
| Boiling point | 107 °C(lit.) |
| Density | 1.626 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.447(lit.) |
| Vapour pressure | 5.57 psi (20 °C) |
| Melting point | −44 °C(lit.) |
| Storage temperature | 2-8°C |
| Application | • Chlorosulfonyl isocyanate was used in synthesis and biochemical characterization of new class of membrane-associated glycosyltransferase inhibitors1.• It is synthetically versatile reagent2 and was used in the preparation of amides3, lactams4,5 and triazocinones6.• It was employed in regio- and diastereoselective introduction of a protected amino group in synthesis of chiral, polyhydroxylated piperidines7.• It was used as reagent during the synthesis of novel sulfamides8. |



Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-22-34-42 |
| Safety statements (S) | 23-26-30-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ABCB1(5243), FPR1(2357) |
|---|
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorosulfonyl isocyanate?
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Chlorosulfonyl isocyanate (CAS 1189-71-5), molecular formula ClSO2NCO, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.
What grades of Chlorosulfonyl isocyanate does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlorosulfonyl isocyanate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of Chlorosulfonyl isocyanate?
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Chlorosulfonyl isocyanate has CAS number 1189-71-5 and molecular formula ClSO2NCO. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for Chlorosulfonyl isocyanate?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of Chlorosulfonyl isocyanate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should Chlorosulfonyl isocyanate be stored?
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Store Chlorosulfonyl isocyanate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is Chlorosulfonyl isocyanate used for?
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Chlorosulfonyl isocyanate is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for Chlorosulfonyl isocyanate?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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