Alosetron hydrochloride
Alosetron hydrochloride (CAS: 122852-69-1), with the molecular formula C17H18N4O·HCl and a molecular weight of 330.81, is a potent and selective serotonin 5-HT3 receptor antagonist. This white to beige powder is primarily utilised in scientific research and development. Its specific pharmacological profile makes it a valuable tool for investigating serotonergic pathways in various biological systems, particularly within neuroscience and cell signalling studies.
- IUPAC
- 2,3,4,5-Tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-pyrido[4,3-b]indol-1-one hydrochloride

Research and Development
Utilised in academic and industrial laboratories for in vitro and in vivo research studies. Its role as a 5-HT3 antagonist aids in understanding neurotransmitter functions and associated physiological processes.
Pharmacological Tool
Serves as a critical reagent for researchers investigating the complex mechanisms of the central and peripheral nervous systems. It helps in probing the effects of serotonin modulation.
Neuroscience Studies
Employed in the study of neurological disorders and neurotransmission, Alosetron hydrochloride assists in dissecting the roles of serotonin receptors in brain function and behaviour.
Cell Biology Investigations
Applied in cell-based assays to explore cellular responses mediated by serotonin receptors, contributing to a deeper understanding of cell signalling pathways.
| Molecular weight | 330.81 |
|---|---|
| Empirical formula | C17H18N4O·HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | H2O: ≥5 mg/mL at warmed |
| Storage temperature | 2-8°C |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P273Avoid release to the environment
- P301IF SWALLOWED
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Alosetron hydrochloride used for?
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Alosetron hydrochloride (CAS: 122852-69-1) is primarily used as a research chemical for investigating serotonin pathways, particularly in neuroscience and cell signalling studies.
What are the CAS number and molecular formula for Alosetron hydrochloride?
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The CAS number for Alosetron hydrochloride is 122852-69-1, and its molecular formula is C17H18N4O·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Alosetron hydrochloride with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should Alosetron hydrochloride be handled?
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Alosetron hydrochloride is classified as a Warning substance (GHS07) and may cause eye irritation (H319). Handle with appropriate personal protective equipment, avoiding contact with eyes and skin. Store in a desiccated environment at 2-8°C.
Is Alosetron hydrochloride a controlled substance?
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The provided data does not indicate that Alosetron hydrochloride is a controlled substance.
How is Alosetron hydrochloride packed and shipped?
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Alosetron hydrochloride is supplied as a powder and is carefully packed for safe handling, storage, and global export, adhering to all relevant shipping regulations.
How can I request a sample or quote for Alosetron hydrochloride?
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To request a sample or quote, please contact our sales team through the TSS website or by phone, providing the product name and CAS number (122852-69-1).
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