GW2974
GW2974 (CAS: 202272-68-2), with the molecular formula C23H21N7 and a molecular weight of 395.46 g/mol, is a potent research chemical. It functions as an Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitor. This yellow solid compound is primarily utilised in cancer research and cell signalling studies, aiding investigations into cellular pathways and disease mechanisms.
- IUPAC
- N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido[3,4-d]pyrimidine-4,6-diamine
Cancer Research
GW2974 serves as a valuable tool in oncology research, specifically targeting the EGFR pathway. Its inhibitory activity helps researchers explore mechanisms of cancer cell proliferation and survival, and evaluate potential therapeutic strategies.
Cell Biology and Signalling
As a selective EGFR tyrosine kinase inhibitor, GW2974 is instrumental in studying cell growth, differentiation, and survival signalling pathways. It aids in understanding the intricate roles of EGFR in normal and pathological cellular processes.
Drug Discovery and Development
GW2974, an approved therapeutic candidate, is used in preclinical research to investigate novel treatments for EGFR-driven malignancies. Its well-characterised inhibitory profile makes it a useful reference compound in the development of new kinase inhibitors.
| Molecular weight | 395.46 |
|---|---|
| Empirical formula | C23H21N7 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | yellow |
| Solubility | DMSO: ≥20 mg/mL |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... EGFR(1956), ERBB2(2064) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GW2974 primarily used for?
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GW2974 is primarily used in cancer research, cell biology, and cell signalling studies as a selective inhibitor of the Epidermal Growth Factor Receptor (EGFR) tyrosine kinase.
What is the CAS number and molecular formula for GW2974?
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The CAS number for GW2974 is 202272-68-2, and its molecular formula is C23H21N7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies GW2974 with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, or EP grade.
How should GW2974 be handled safely?
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Safe handling of GW2974 requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Consult the safety data sheet for comprehensive handling guidelines.
Is GW2974 a controlled substance?
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The provided data does not indicate that GW2974 is a controlled substance.
How is GW2974 packed and shipped?
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GW2974 is supplied as a yellow solid. It is carefully packed to ensure stability during transport and is exported globally by Tech Serve Solutions.
How can I request a quote or sample for GW2974?
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To request a quote or sample for GW2974, please contact the Tech Serve Solutions sales team through our website or via email.
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