GTS-21

CAS 156223-05-1C19H20N2O2 · 2HClCell Biology

GTS-21 (CAS: 156223-05-1), with the molecular formula C19H20N2O2 · 2HCl and a molecular weight of 381.30 g/mol, is supplied by Tech Serve Solutions as a faint yellow to dark yellow powder. This compound functions as a selective agonist for the alpha-7 nicotinic acetylcholine receptor (α7 nAChR). It is primarily utilised in research settings for investigating cholinergic pathways, neurotransmission, and cellular signalling, particularly within neuroscience and cell biology.

IUPAC: 3-(2,4-Dimethoxybenzylidene)-anabaseine dihydrochloride,DMBX-anabaseine,DMXB-A,DMXB,GTS21
Synonyms: 3-(2,4-Dimethoxybenzylidene)-anabaseine dihydrochlorideDMBX-anabaseineDMXB-ADMXBGTS21

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GTS-21 (C19H20N2O2 · 2HCl) — chemical structure, CAS 156223-05-1; Life Science, fine chemical supplied by Tech Serve Solutions

AgonistsCell BiologyCholinergicsIon ChannelsLigand-Gated Ion ChannelsNeuroscienceNeurotransmissionNeurotransmitters

01 /Applications

Neuroscience Research

GTS-21 is extensively used to probe the function of alpha-7 nicotinic acetylcholine receptors in the central nervous system. Its selective agonistic activity aids in studying neurotransmission and neuronal signalling pathways relevant to cognitive processes and neurological disorders.

Cell Biology and Signalling

As a key tool in cell biology, GTS-21 helps researchers investigate the role of α7 nAChRs in various cellular functions. It is instrumental in understanding cell signalling cascades and the effects of cholinergic modulation on cellular responses.

Ligand-Gated Ion Channel Studies

This compound serves as a valuable research chemical for characterising the activity and modulation of ligand-gated ion channels, specifically the nicotinic acetylcholine receptors. Its interaction with the α7 subtype provides insights into ion channel gating mechanisms.

02 /Properties

Molecular weight	381.30
Empirical formula	C19H20N2O2 · 2HCl
Assay	≥97% (HPLC)
Form	powder
Colour	faint yellow to dark yellow
Solubility	H2O: >5 mg/mL
Storage temperature	2-8°C

03 /Identifiers & registry

CAS number

156223-05-1

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is GTS-21 used for?

GTS-21 is primarily used in research for studying the function of alpha-7 nicotinic acetylcholine receptors (α7 nAChR), investigating neurotransmission, cell signalling, and as a tool in neuroscience and cell biology research.

What are the CAS number and chemical formula for GTS-21?

The CAS number for GTS-21 is 156223-05-1, and its chemical formula is C19H20N2O2 · 2HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies GTS-21 with a purity of ≥97% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.

How should GTS-21 be handled and stored safely?

GTS-21 is classified under WGK Germany 2, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area. Store refrigerated at 2-8°C.

Is GTS-21 a controlled substance?

The provided data does not indicate that GTS-21 is a controlled substance. However, users should always verify local regulations.

How is GTS-21 packed, shipped, and exported?

Tech Serve Solutions carefully packs and ships GTS-21 according to international regulations for chemical transport. We are a global supplier and exporter.