GW0742
GW0742 (CAS 317318-84-6), with the molecular formula C21H17F4NO3S2 and a molecular weight of 471.49, is a research chemical primarily utilised for its role as a potent PPARδ agonist. This compound plays a significant role in scientific research, particularly in studies investigating metabolic pathways, cellular energy regulation, and potential therapeutic applications in conditions related to lipid metabolism and mitochondrial function. It is supplied as a white solid.
- IUPAC
- 4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-ylmethylsulfanyl]- 2-methyl-phenoxy}-acetic acid
PPARδ Agonist Research
GW0742 is a highly selective and potent agonist for the peroxisome proliferator-activated receptor delta (PPARδ). It is widely used in preclinical research to investigate the physiological roles of PPARδ in energy metabolism, glucose homeostasis, and fatty acid oxidation.
Cellular Metabolism Studies
Researchers employ GW0742 to explore its effects on mitochondrial biogenesis, cellular respiration, and substrate utilisation in various cell types. This helps elucidate pathways involved in endurance, exercise mimetics, and metabolic disease models.
Drug Discovery and Development
As a well-characterised PPARδ agonist, GW0742 serves as a valuable tool in early-stage drug discovery. It aids in the screening of novel compounds and the validation of therapeutic targets for metabolic and cardiovascular conditions.
| Molecular weight | 471.49 |
|---|---|
| Empirical formula | C21H17F4NO3S2 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >5 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Melting point | 134.5-135.5 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PPARA(5465), PPARD(5467), PPARG(5468) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GW0742 used for?
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GW0742 is primarily used in scientific research as a potent PPARδ agonist to study its effects on cellular metabolism, energy regulation, and potential therapeutic applications in metabolic and cardiovascular diseases.
What are the CAS number and molecular formula for GW0742?
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The CAS number for GW0742 is 317318-84-6, and its molecular formula is C21H17F4NO3S2.
What grade and purity does Tech Serve Solutions supply for GW0742?
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Tech Serve Solutions supplies GW0742 with an assay of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the safety precautions for handling GW0742?
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When handling GW0742, it is essential to use appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Handle in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive information.
How is GW0742 shipped and exported?
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GW0742 is carefully packed and exported by Tech Serve Solutions in compliance with all relevant international shipping regulations for research chemicals.
How can I request a quote or sample for GW0742?
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To request a quote or a sample of GW0742, please contact our sales department through the website or via direct inquiry, providing your research requirements.
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