Fmoc-N-Me-D-Ala-OH
Fmoc-N-Me-D-Ala-OH (CAS: 138774-92-2, C19H19NO4) is a protected unnatural amino acid derivative. With a molecular weight of 325.36 g/mol, it features the Fmoc protecting group on the amine nitrogen and a methyl group on the alpha-carbon of D-alanine. This compound is primarily utilised in peptide synthesis, particularly for creating modified peptides with altered conformational or biological properties, and serves as a valuable building block in chemical biology and medicinal chemistry research.
- IUPAC
- Fmoc-N-methyl-D-alanine
- Synonyms
- Fmoc-N-methyl-D-alanine
Peptide Synthesis
Fmoc-N-Me-D-Ala-OH is employed as a building block in solid-phase and solution-phase peptide synthesis. Its incorporation allows for the introduction of N-methylated and unnatural D-amino acid residues into peptide chains, influencing secondary structure and proteolytic stability.
Chemical Biology Research
This unnatural amino acid derivative is used to explore structure-activity relationships in peptides and peptidomimetics. Its unique structural features can impart novel biological functions or modify existing ones for research purposes.
Medicinal Chemistry
In medicinal chemistry, Fmoc-N-Me-D-Ala-OH can be incorporated into drug candidates to enhance pharmacokinetic properties, such as increased oral bioavailability or resistance to enzymatic degradation.
Analytical Standards
As a well-characterised chemical entity, it may also find application as an analytical standard in chromatography and other analytical techniques for the identification and quantification of related compounds.
| Molecular weight | 325.36 |
|---|---|
| Empirical formula | C19H19NO4 |
| Assay | ≥98.0% (TLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-N-Me-D-Ala-OH used for?
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Fmoc-N-Me-D-Ala-OH is primarily used as a protected unnatural amino acid building block in peptide synthesis, chemical biology research, and medicinal chemistry to introduce N-methylated D-alanine residues.
What is the CAS number and molecular formula for Fmoc-N-Me-D-Ala-OH?
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The CAS number is 138774-92-2 and the molecular formula is C19H19NO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-N-Me-D-Ala-OH?
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Tech Serve Solutions supplies Fmoc-N-Me-D-Ala-OH with a purity of ≥98.0% (TLC). We do not represent this product as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling recommendations for Fmoc-N-Me-D-Ala-OH?
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When handling Fmoc-N-Me-D-Ala-OH, it is recommended to use Eyeshields and Gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if respiratory protection is needed. The compound is classified under WGK Germany 3, indicating a high hazard to water.
How is Fmoc-N-Me-D-Ala-OH stored and shipped?
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Fmoc-N-Me-D-Ala-OH should be stored at 2-8°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a quote or sample for Fmoc-N-Me-D-Ala-OH?
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Please contact our sales team or use the online inquiry form on the Tech Serve Solutions website to request a quote or a sample of Fmoc-N-Me-D-Ala-OH.
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