Fmoc-N-Me-D-Phe-OH

CAS 138775-05-0C25H23NO4Chemical Synthesis

Fmoc-N-Me-D-Phe-OH (CAS 138775-05-0), with molecular formula C25H23NO4 and a molecular weight of 401.45, is a specialised N-methyl amino acid derivative. It is a valuable building block in chemical synthesis and peptide chemistry. This compound finds application in chemical biology research and the development of unnatural amino acid derivatives, supporting advanced molecular design and discovery in various scientific fields.

IUPAC: Fmoc-N-methyl-D-phenylalanine
Synonyms: Fmoc-N-methyl-D-phenylalanine

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Fmoc-N-Me-D-Phe-OH (C25H23NO4) — chemical structure, CAS 138775-05-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisN-Methyl Amino AcidsPeptide Chemistry

01 /Applications

Peptide Synthesis

Fmoc-N-Me-D-Phe-OH serves as a protected unnatural amino acid derivative for incorporation into peptide chains. Its N-methyl modification offers unique conformational properties to the resulting peptides.

Chemical Biology Research

This compound is utilised in chemical biology to synthesise modified peptides or peptidomimetics. These molecules can be used to probe biological pathways or as research tools in drug discovery.

Development of Unnatural Amino Acids

It acts as a key intermediate in the synthesis of novel, non-proteinogenic amino acids. Such derivatives are essential for expanding the chemical diversity available for biomolecular engineering.

Chemical Synthesis Building Block

As a chiral building block, Fmoc-N-Me-D-Phe-OH is employed in complex organic synthesis. Its protected nature facilitates selective reactions in multi-step synthetic strategies.

02 /Properties

Molecular weight	401.45
Empirical formula	C25H23NO4
Assay	≥98.0% (HPLC)
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

138775-05-0

MDL number

MFCD00153392

Beilstein registry

8441627

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-N-Me-D-Phe-OH used for?

Fmoc-N-Me-D-Phe-OH is used as a protected unnatural amino acid derivative in peptide synthesis, chemical biology research, and as a building block for the creation of novel amino acid derivatives and complex molecules.

What are the CAS number and molecular formula for Fmoc-N-Me-D-Phe-OH?

The CAS number is 138775-05-0, and the molecular formula is C25H23NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-N-Me-D-Phe-OH with an assay of ≥98.0% (HPLC). This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.

What are the safety and handling recommendations for Fmoc-N-Me-D-Phe-OH?

According to GHS classifications, this compound has a WGK Germany rating of 3. Recommended personal protective equipment includes eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter for adequate protection.

How is Fmoc-N-Me-D-Phe-OH stored and shipped?

Fmoc-N-Me-D-Phe-OH should be stored at temperatures between 2-8°C. Tech Serve Solutions exports chemicals globally, ensuring appropriate packaging and handling for safe international transit.

How can I request a quote or sample?

To request a quote or a sample of Fmoc-N-Me-D-Phe-OH, please contact our sales department through the website or direct email, providing your specific requirements.