Fmoc-N-Me-Asn(Trt)-OH
Fmoc-N-Me-Asn(Trt)-OH (CAS 941296-80-6) is a protected N-methylated amino acid derivative with the molecular formula C39H34N2O5. This compound is essential for specialised applications in chemical biology and peptide synthesis. Utilised in the construction of complex peptide chains, it incorporates N-methylation and specific side-chain protection, facilitating the study of modified peptides and their biological interactions.
Peptide Synthesis
Fmoc-N-Me-Asn(Trt)-OH is employed in solid-phase and solution-phase peptide synthesis. Its Fmoc protecting group allows for orthogonal deprotection strategies, while the N-methyl and Trityl groups offer specific steric and electronic properties to the resulting peptide.
Chemical Biology Research
This unnatural amino acid derivative is used to introduce specific modifications into peptides for studying structure-activity relationships, protein-ligand interactions, and developing novel bioactive molecules. The N-methylation can influence peptide conformation and stability.
Drug Discovery and Development
Incorporation of N-methylated amino acids like Fmoc-N-Me-Asn(Trt)-OH can enhance the metabolic stability and bioavailability of peptide-based therapeutics. It aids in the design of more robust and effective drug candidates.
| Molecular weight | 610.70 |
|---|---|
| Empirical formula | C39H34N2O5 |
| Assay | 97% (HPLC) |
| Optical activity | [α]22/D -26.0°, c = 0.5% in dichloromethane |
| Storage temperature | 2-8°C |
| Melting point | 231-235 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-N-Me-Asn(Trt)-OH used for?
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Fmoc-N-Me-Asn(Trt)-OH is primarily used in specialised peptide synthesis and chemical biology research for creating modified peptides with enhanced properties like metabolic stability and altered conformation.
What are the CAS number and formula for Fmoc-N-Me-Asn(Trt)-OH?
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The CAS number is 941296-80-6, and its empirical formula (Hill notation) is C39H34N2O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-N-Me-Asn(Trt)-OH with a purity of 97% (HPLC). This product is intended for research and development purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-N-Me-Asn(Trt)-OH be handled and stored?
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This compound has a GHS classification indicating it is hazardous. It should be handled with appropriate personal protective equipment in a well-ventilated area. Store refrigerated at 2-8°C to maintain stability.
Is this compound a controlled substance?
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The provided data does not indicate that Fmoc-N-Me-Asn(Trt)-OH is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Packaging and shipping comply with international regulations for hazardous materials. Please contact us for specific export details.
How can I request a sample or quote?
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To request a sample or a formal quotation for Fmoc-N-Me-Asn(Trt)-OH, please use the contact form on our website or email our sales department, providing your required quantity and shipping details.
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