Fmoc-N-Me-Aib-OH
Fmoc-N-Me-Aib-OH (CAS 400779-65-9) is an N-methylated amino acid derivative with the molecular formula C20H21NO4 and a molecular weight of 339.39 g/mol. It is commonly employed in peptide chemistry and chemical synthesis due to its unnatural amino acid structure. This compound serves as a valuable building block for researchers exploring novel peptide structures and peptidomimetics.
- IUPAC
- N-Fmoc-α-(methylamino)isobutyric acid,Fmoc-N,2-dimethylalanine
- Synonyms
- N-Fmoc-α-(methylamino)isobutyric acidFmoc-N,2-dimethylalanine

Peptide Synthesis
Fmoc-N-Me-Aib-OH is utilised in the synthesis of peptides containing N-methylated amino acid residues. These modifications can influence peptide conformation, stability, and biological activity.
Chemical Biology Research
As an unnatural amino acid derivative, it can be incorporated into peptides to probe structure-activity relationships or to develop peptidomimetics with altered pharmacological profiles.
Organic Synthesis
This compound serves as a chiral building block in complex organic synthesis pathways, enabling the construction of diverse molecular architectures.
| Molecular weight | 339.39 |
|---|---|
| Empirical formula | C20H21NO4 |
| Assay | ≥96.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-N-Me-Aib-OH used for?
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Fmoc-N-Me-Aib-OH is primarily used in peptide synthesis and chemical biology research as a building block for creating peptides containing unnatural N-methylated amino acid residues.
What is the CAS number and molecular formula for Fmoc-N-Me-Aib-OH?
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The CAS number is 400779-65-9 and the molecular formula is C20H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-N-Me-Aib-OH with an assay of ≥96.0%. This product is intended for research and laboratory use. We do not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should Fmoc-N-Me-Aib-OH be handled and stored?
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Handle Fmoc-N-Me-Aib-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Store at 2-8°C.
Is this product a controlled substance?
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The provided data does not indicate that Fmoc-N-Me-Aib-OH is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, adhering to all relevant shipping regulations for chemical products.
How can I request a quote or sample?
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Please contact our sales team through the website to request a quotation or inquire about sample availability.
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