Fmoc-N-(2,4-dimethoxybenzyl)-Gly-OH
Fmoc-N-(2,4-dimethoxybenzyl)-Gly-OH (CAS: 166881-42-1), a glycine derivative with the molecular formula C26H25NO6, is a specialised reagent for chemical synthesis. It finds application in peptide chemistry and the development of unnatural amino acid derivatives. This compound is supplied by Tech Serve Solutions with an assay of ≥98.0% (HPLC) and requires storage at 2-8°C. It is primarily utilised in research and development settings for complex organic molecule construction.
- IUPAC
- Fmoc-N-(2,4-dimethoxybenzyl)glycine,Fmoc-Dmb-Gly-OH
- Synonyms
- Fmoc-Dmb-Gly-OHFmoc-N-(2,4-dimethoxybenzyl)glycine

Peptide Synthesis
Fmoc-N-(2,4-dimethoxybenzyl)-Gly-OH serves as a building block in solid-phase and solution-phase peptide synthesis. Its structure allows for controlled incorporation into peptide chains, particularly when employing the Fmoc strategy.
Unnatural Amino Acid Derivatives
This compound is valuable for synthesising modified or unnatural amino acids. The dimethoxybenzyl group offers unique protecting group characteristics that can be advantageous in complex synthetic routes.
Chemical Biology Research
Researchers in chemical biology utilise this reagent to create novel peptides or peptidomimetics for studying biological processes. Its specific structure can be incorporated to probe protein-ligand interactions or enzyme mechanisms.
Organic Synthesis
As a functionalised glycine derivative, it is employed in general organic synthesis for the construction of complex molecules requiring specific chiral or protected amino acid fragments.
| Molecular weight | 447.48 |
|---|---|
| Empirical formula | C26H25NO6 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-N-(2,4-dimethoxybenzyl)-Gly-OH used for?
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Fmoc-N-(2,4-dimethoxybenzyl)-Gly-OH is primarily used as a building block in peptide synthesis, for creating unnatural amino acid derivatives, and in various applications within chemical biology and organic synthesis research.
What is the CAS number and molecular formula for Fmoc-N-(2,4-dimethoxybenzyl)-Gly-OH?
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The CAS number is 166881-42-1, and the molecular formula is C26H25NO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-N-(2,4-dimethoxybenzyl)-Gly-OH with a purity of ≥98.0% as determined by HPLC. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound may cause long lasting harmful effects to aquatic life (H413). Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended if airborne exposure is possible. Handle in a well-ventilated area.
How is Fmoc-N-(2,4-dimethoxybenzyl)-Gly-OH typically supplied and exported?
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This chemical is carefully packaged for stable storage at 2-8°C. Tech Serve Solutions, as a global supplier and exporter, ensures appropriate handling and documentation for international shipments.
How can I request a quote or sample?
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To request a quote or a sample of Fmoc-N-(2,4-dimethoxybenzyl)-Gly-OH, please contact the Tech Serve Solutions sales team via our website or listed contact details.
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