Fmoc-Met-OPfp
Fmoc-Met-OPfp (CAS 86060-94-8), with the molecular formula C26H20F5NO4S and a molecular weight of 537.50, is a protected amino acid derivative. It is primarily utilised in solid-phase peptide synthesis (SPPS) and other organic chemistry applications where controlled introduction of methionine is required. Its pentafluorophenyl ester group facilitates efficient coupling reactions under standard peptide synthesis conditions.
- IUPAC
- Fmoc-L-methionine pentafluorophenyl ester

Solid-Phase Peptide Synthesis (SPPS)
Fmoc-Met-OPfp is a key building block in SPPS, enabling the sequential addition of methionine residues to a growing peptide chain. The Fmoc protecting group ensures orthogonal protection strategy, allowing for selective deprotection and coupling cycles.
Chemical Biology Research
This compound can be employed in research exploring protein structure-function relationships or developing novel peptide-based therapeutics. Its specific modifications allow for targeted incorporation into biomolecules.
Organic Synthesis
Beyond peptide synthesis, Fmoc-Met-OPfp serves as a versatile reagent in complex organic synthesis, facilitating the introduction of functionalised methionine moieties into various molecular scaffolds.
| Molecular weight | 537.50 |
|---|---|
| Empirical formula | C26H20F5NO4S |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Met-OPfp used for?
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Fmoc-Met-OPfp is used as a protected amino acid building block, primarily in solid-phase peptide synthesis (SPPS), chemical biology research, and general organic synthesis for introducing methionine.
What is the CAS number and formula for Fmoc-Met-OPfp?
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The CAS number is 86060-94-8, and the empirical formula (Hill notation) is C26H20F5NO4S.
What grade and purity does Tech Serve Solutions supply for Fmoc-Met-OPfp?
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Tech Serve Solutions supplies Fmoc-Met-OPfp with a purity of ≥96.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Fmoc-Met-OPfp be handled and stored?
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Handle Fmoc-Met-OPfp with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. Store at 2-8°C to maintain stability.
Is Fmoc-Met-OPfp a controlled substance?
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Based on the provided data, there is no indication that Fmoc-Met-OPfp is a controlled substance.
How is Fmoc-Met-OPfp packed, shipped, and exported?
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Fmoc-Met-OPfp is available from Tech Serve Solutions, a global supplier and exporter, packed and shipped according to standard chemical handling protocols to ensure integrity during transit.
How can I request a quote or sample for Fmoc-Met-OPfp?
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Please contact our sales team directly via the website or listed contact details to request a quote or sample of Fmoc-Met-OPfp.
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