Fmoc-Lys-OH hydrochloride
Nα-Fmoc-L-lysine hydrochloride (CAS: 139262-23-0; C21H24N2O4 · HCl; MW: 404.89) is a protected amino acid derivative used in peptide synthesis. It features the Fmoc group, a base-labile protecting group for the N-terminus, and the hydrochloride salt of lysine. This compound is vital for the controlled, sequential addition of lysine residues into peptide chains during solid-phase peptide synthesis (SPPS) and solution-phase methodologies.
- IUPAC
- Nα-Fmoc-L-lysine hydrochloride
- Synonyms
- Nα-Fmoc-L-lysine hydrochloride
Peptide Synthesis
Nα-Fmoc-L-lysine hydrochloride is a key building block in the synthesis of peptides. The Fmoc protecting group allows for selective deprotection and coupling, enabling the controlled incorporation of lysine into growing peptide chains for various research and therapeutic applications.
Chemical Biology Research
This derivative is employed in chemical biology to introduce lysine residues with specific modifications or conjugations. It facilitates the study of protein-lysine interactions and the development of novel biomolecules.
Organic Synthesis
Beyond peptide chemistry, Nα-Fmoc-L-lysine hydrochloride serves as a chiral synthon in complex organic synthesis. Its functional groups can be selectively manipulated for the construction of intricate molecular architectures.
| Molecular weight | 404.89 |
|---|---|
| Empirical formula | C21H24N2O4 · HCl |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Fmoc-L-lysine hydrochloride used for?
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Nα-Fmoc-L-lysine hydrochloride is primarily used as a protected amino acid building block in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) and solution-phase methods. It allows for the controlled incorporation of lysine residues into peptide sequences for research and pharmaceutical development.
What are the CAS number and molecular formula for Nα-Fmoc-L-lysine hydrochloride?
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The CAS number is 139262-23-0, and the molecular formula is C21H24N2O4 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nα-Fmoc-L-lysine hydrochloride with a purity of ≥98.0% as determined by HPLC. This product is supplied for research and laboratory use. TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What safety precautions should be taken when handling Nα-Fmoc-L-lysine hydrochloride?
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When handling Nα-Fmoc-L-lysine hydrochloride, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended if airborne exposure is possible. The substance has a WGK Germany rating of 3, indicating a high hazard to water.
How is Nα-Fmoc-L-lysine hydrochloride shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Nα-Fmoc-L-lysine hydrochloride is carefully packed and exported worldwide in compliance with international shipping regulations for chemical substances.
How can I request a sample or quote for Nα-Fmoc-L-lysine hydrochloride?
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To request a sample or a quotation for Nα-Fmoc-L-lysine hydrochloride, please visit the Tech Serve Solutions website or contact our sales department directly with your specific requirements.
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