trans-4-Hydroxy-L-proline

CAS 51-35-4C5H9NO3Chemical Synthesis

trans-4-Hydroxy-L-proline (CAS: 51-35-4, C5H9NO3) is a non-essential amino acid and a key component of collagen. With a molecular weight of 131.13 g/mol, this compound is vital for the structural integrity of connective tissues. It is widely utilized in biochemical research, cell culture applications, and as a building block in chemical synthesis, contributing to advancements in various scientific disciplines.

IUPAC: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid,Hyp
Synonyms: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acidHyp

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trans-4-Hydroxy-L-proline (C5H9NO3) — chemical structure, CAS 51-35-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Aloe VeraAmino AcidAmino Acid LibraryAmino AcidsAmino Acids and VitaminsCell BiologyCell CultureChemical BiologyChemical SynthesisMetabolic Libraries

01 /Applications

Biochemical Research

As a fundamental amino acid, trans-4-Hydroxy-L-proline serves as a crucial research tool in understanding protein structure, function, and metabolism. Its role in collagen synthesis makes it invaluable for studies on connective tissue disorders and wound healing.

Cell Culture

This compound is cell culture tested and widely used as a supplement in cell culture media. It supports the growth and maintenance of various cell types, particularly those involved in collagen production and extracellular matrix formation.

Chemical Synthesis

trans-4-Hydroxy-L-proline acts as a chiral building block in organic synthesis. Its unique structure allows for the development of novel pharmaceuticals, peptides, and other complex organic molecules.

02 /Properties

Molecular weight	131.13
Empirical formula	C5H9NO3
Assay	≥99%
Optical activity	[α]25/D −75.6°, c = 1 in H2O
Suitability	cell culture tested
Melting point	273 °C (dec.)(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

51-35-4

MDL number

MFCD00064320

PubChem substance

24895700

Beilstein registry

81441

05 /Additional specifications

Product Line	BioReagent

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is trans-4-Hydroxy-L-proline used for?

trans-4-Hydroxy-L-proline is primarily used in biochemical research, as a supplement in cell culture media to support cellular growth and matrix formation, and as a chiral building block in chemical synthesis.

What is the CAS number and formula for trans-4-Hydroxy-L-proline?

The CAS number for trans-4-Hydroxy-L-proline is 51-35-4, and its empirical formula is C5H9NO3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies trans-4-Hydroxy-L-proline with a purity of ≥99%. It is tested for suitability in cell culture. This product is not represented as USP, BP, EP, or pharmacopoeia grade.

What are the safety and handling recommendations for trans-4-Hydroxy-L-proline?

When handling trans-4-Hydroxy-L-proline, it is recommended to use eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary. The compound has a WGK rating of 3 in Germany, indicating a high hazard to water.

How is trans-4-Hydroxy-L-proline packed and exported?

trans-4-Hydroxy-L-proline is carefully packed to ensure stability during transit and is available for global export. Specific packaging details will be provided upon inquiry.