trans-4-Hydroxy-D-proline
trans-4-Hydroxy-D-proline (CAS: 3398-22-9, C5H9NO3) is a non-proteinogenic amino acid featuring a hydroxyl group on the pyrrolidine ring. Its chiral structure makes it a valuable building block in asymmetric synthesis and peptide chemistry. Available from Tech Serve Solutions with a 97% assay, this compound is essential for researchers developing novel pharmaceuticals and advanced materials.
- IUPAC
- (2R,4S)-4-Hydroxypyrrolidine-2-carboxylic acid
Chiral Building Block in Synthesis
Utilised as a chiral synthon for the construction of complex organic molecules, particularly in the development of stereoselective pharmaceuticals and natural products. Its defined stereochemistry is critical for achieving desired biological activity.
Peptide Chemistry
Incorporated into synthetic peptides to introduce specific structural constraints and enhance stability or biological function. Hydroxyproline derivatives are key components in collagen mimetics and other peptidomimetics.
Asymmetric Synthesis
Serves as a versatile precursor for asymmetric catalysts and chiral auxiliaries, enabling the enantioselective synthesis of various target compounds.
Chemical Biology Research
Employed in probing biological pathways and understanding protein structure-function relationships, particularly those involving collagen and proline-rich motifs.
| Molecular weight | 131.13 |
|---|---|
| Empirical formula | C5H9NO3 |
| Assay | 97% |
| Melting point | 261 °C (dec) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is trans-4-Hydroxy-D-proline used for?
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trans-4-Hydroxy-D-proline is primarily used as a chiral building block in asymmetric synthesis, in peptide chemistry, and in chemical biology research for developing pharmaceuticals and other complex organic molecules.
What is the CAS number and formula for trans-4-Hydroxy-D-proline?
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The CAS number for trans-4-Hydroxy-D-proline is 3398-22-9, and its empirical formula is C5H9NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies trans-4-Hydroxy-D-proline with a purity of 97%. This product is typically supplied for research and laboratory use. We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should trans-4-Hydroxy-D-proline be handled safely?
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trans-4-Hydroxy-D-proline is labelled with Danger. It may cause respiratory irritation, and is harmful if swallowed, causes skin irritation and serious eye irritation. Handling requires a dust mask type N95 (US), eyeshields, faceshields, and gloves. Ensure good ventilation and avoid dust formation. Refer to the Safety Data Sheet (SDS) for full details.
Can Tech Serve Solutions export trans-4-Hydroxy-D-proline internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including trans-4-Hydroxy-D-proline, and can facilitate international shipments.
How can I request a sample or quote for trans-4-Hydroxy-D-proline?
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To request a sample or obtain a quote for trans-4-Hydroxy-D-proline, please contact our sales department through the website or by phone.
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