4-Thiouracil
4-Thiouracil (CAS: 591-28-6, C4H4N2OS) is a heterocyclic organic compound with a molecular weight of 128.15 g/mol. This pyrimidine derivative is a valuable building block in organic synthesis. It is primarily used in research and chemical synthesis, particularly for the preparation of more complex molecules and heterocyclic structures. Available at a purity of 97%, it serves as a key intermediate for various chemical transformations.
- IUPAC
- 2-Hydroxy-4-mercaptopyrimidine

Organic Synthesis Intermediate
4-Thiouracil serves as a crucial intermediate in the synthesis of various organic compounds. Its structure allows for diverse chemical modifications, making it a versatile component in multi-step synthetic pathways.
Heterocyclic Chemistry Research
As a pyrimidine derivative, 4-Thiouracil is employed in research focused on heterocyclic chemistry. It is used to explore novel chemical reactions and to construct new heterocyclic frameworks.
Biochemical Research
This compound finds applications in biochemical research, often as a precursor or analogue in studies involving nucleic acid bases and their derivatives.
| Molecular weight | 128.15 |
|---|---|
| Empirical formula | C4H4N2OS |
| Assay | 97% |
| Melting point | 295 °C (dec.)(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Thiouracil used for?
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4-Thiouracil is used as a building block in organic synthesis, particularly in heterocyclic chemistry and biochemical research for creating novel compounds and exploring chemical transformations.
What is the CAS number and formula for 4-Thiouracil?
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The CAS number for 4-Thiouracil is 591-28-6, and its empirical formula is C4H4N2OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Thiouracil with an assay of 97%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 4-Thiouracil be handled safely?
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4-Thiouracil (CAS: 591-28-6) is classified as harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Handle in a well-ventilated area. Refer to the Safety Data Sheet for full handling instructions.
Is 4-Thiouracil a controlled substance?
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The provided data does not indicate that 4-Thiouracil is a controlled substance.
How is 4-Thiouracil packed and exported?
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4-Thiouracil is packed according to industry standards for chemical reagents and is available for global export by Tech Serve Solutions.
How can I request a quote or sample for 4-Thiouracil?
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To request a quote or sample for 4-Thiouracil, please contact the Tech Serve Solutions sales team through our website or designated contact channels.
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