4-Thioanisolemagnesium bromide solution
4-Thioanisolemagnesium bromide solution (CAS: 18620-04-7), with the linear formula H₃CSC₆H₄MgBr, is an organometallic compound. This Grignard reagent, supplied as a 0.5 M solution in THF, is a valuable tool in organic synthesis. Its primary application lies in introducing the 4-methylthiophenyl group into various organic molecules through nucleophilic addition reactions, facilitating the construction of complex chemical structures.
Organosulfur Compound Synthesis
Utilized as a key reagent for the introduction of the 4-methylthiophenyl moiety into organic frameworks. This facilitates the synthesis of diverse organosulfur compounds with potential applications in pharmaceuticals and materials science.
Grignard Reaction Intermediate
Serves as a nucleophilic source of the 4-methylthiophenyl anion in Grignard reactions. It readily reacts with electrophiles such as aldehydes, ketones, esters, and epoxides to form new carbon-carbon bonds.
Pharmaceutical Intermediate Synthesis
A building block in the multi-step synthesis of complex organic molecules, including potential pharmaceutical intermediates. Its specific reactivity allows for targeted functionalization in drug discovery programmes.
Aryl Group Introduction
Enables the efficient introduction of an aryl group bearing a thioether substituent onto various molecular scaffolds, expanding the scope of synthetic strategies.
| Molecular weight | 227.40 |
|---|---|
| Linear formula | H3CSC6H4MgBr |
| Boiling point | 65 °C |
| Density | 0.965 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Thioanisolemagnesium bromide solution used for?
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4-Thioanisolemagnesium bromide solution (CAS: 18620-04-7) is primarily used in organic synthesis for the introduction of the 4-methylthiophenyl group into organic molecules via Grignard reactions. It acts as a nucleophilic reagent to form new carbon-carbon bonds with various electrophiles.
What are the CAS number and formula for 4-Thioanisolemagnesium bromide solution?
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The CAS number is 18620-04-7 and the linear formula is H₃CSC₆H₄MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. We do not represent this product as USP, BP, or EP grade.
How should 4-Thioanisolemagnesium bromide solution be handled?
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This solution is flammable and corrosive. It reacts violently with water and can cause severe skin burns and eye damage. Handle with extreme caution in a well-ventilated area, away from ignition sources. Wear appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
How is 4-Thioanisolemagnesium bromide solution packaged and shipped?
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This chemical is typically packaged in appropriate containers designed for reactive and flammable liquids and shipped according to relevant dangerous goods regulations (UN 2924 8(3) / PGII).
How can I request a sample or quote?
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To request a sample or a quotation, please contact our sales team through the website or by calling our dedicated customer service line. Please reference the product name and CAS number (18620-04-7) in your request.
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