4-Sulfophenyl isothiocyanate sodium salt monohydrate
4-Sulfophenyl isothiocyanate sodium salt monohydrate (CAS: 143193-53-7; Formula: NaO3SC6H4NCS·H2O; MW: 255.25) is a versatile organic building block. This sulfur-containing compound, a derivative of thiocyanates/isothiocyanates, serves as a valuable intermediate in chemical synthesis. Its structure facilitates its use in creating more complex molecules for research and development purposes across various scientific disciplines.
- IUPAC
- 4-Isothiocyanatobenzenesulfonic acid sodium salt monohydrate
- Synonyms
- 4-Isothiocyanatobenzenesulfonic acid sodium salt monohydrate

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of novel organic compounds. Its isothiocyanate functionality allows for diverse reactions, making it valuable for constructing complex molecular architectures in research settings.
Chemical Research and Development
Serves as a reagent in chemical laboratories for exploring new synthetic pathways. Its unique chemical structure contributes to its utility in academic and industrial R&D projects focused on sulfur-containing organic molecules.
Building Block for Specialty Chemicals
Acts as a foundational building block for the development of specialty chemicals. The presence of both a sulfonate group and an isothiocyanate moiety offers multiple points for chemical modification and derivatization.
| Molecular weight | 255.25 |
|---|---|
| Linear formula | NaO3SC6H4NCS·H2O |
| Storage temperature | 2-8°C |

Hazard statements
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 42 |
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Sulfophenyl isothiocyanate sodium salt monohydrate used for?
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It is primarily used as an intermediate and building block in organic synthesis and chemical research and development to create more complex molecules, particularly those containing sulfur.
What is the CAS number and chemical formula for 4-Sulfophenyl isothiocyanate sodium salt monohydrate?
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The CAS number is 143193-53-7 and the chemical formula is NaO3SC6H4NCS·H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research purposes. The specific assay and purity are detailed in the product specifications. We do not represent this product as meeting USP, BP, EP, or pharmacopoeia standards.
How should 4-Sulfophenyl isothiocyanate sodium salt monohydrate be handled?
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Handle with appropriate personal protective equipment including a dust mask (type N95 US recommended), eyeshields, faceshields, and gloves. Avoid breathing dust. Ensure good ventilation. This compound is classified as a respiratory sensitizer (H334).
How is this chemical shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, adhering to all necessary regulations for safe and compliant international shipping.
How can I request a sample or quote?
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Please contact our sales team via the website or phone to request a sample or a formal quotation for 4-Sulfophenyl isothiocyanate sodium salt monohydrate.
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