D(−)-2-Amino-5-phosphonopentanoic acid
D(−)-2-Amino-5-phosphonopentanoic acid (CAS: 79055-68-8; C5H12NO5P) is a chemical compound with a molecular weight of 197.13 g/mol. It functions as an NMDA antagonist and is involved in neurotransmission. This compound is primarily utilized in biochemical research, particularly within cell biology and neuroscience, for investigating excitatory amino acid pathways and receptor activity. Its specific applications leverage its role as a potent inhibitor in neurological research contexts.
- IUPAC
- D(−)-AP-5,D(−)-APV,D-2-Amino-5-phosphonovaleric acid
- Synonyms
- D(−)-AP-5D(−)-APVD-2-Amino-5-phosphonovaleric acid
NMDA Receptor Antagonist Research
D(−)-2-Amino-5-phosphonopentanoic acid is widely employed as a selective antagonist of NMDA receptors. This makes it a valuable tool for researchers studying excitatory neurotransmission and its role in synaptic plasticity, learning, and memory.
Neuroscience and Cell Signaling Studies
The compound aids in dissecting cellular signaling cascades and understanding the function of excitatory amino acids in the nervous system. It is used to investigate mechanisms related to neurodegenerative diseases and neuronal excitotoxicity.
Biochemical and Pharmacological Research
As a well-characterised chemical entity, D(−)-2-Amino-5-phosphonopentanoic acid serves as a standard reagent in biochemical assays and pharmacological investigations aimed at identifying modulators of glutamate receptors.
| Molecular weight | 197.13 |
|---|---|
| Empirical formula | C5H12NO5P |
| Optical purity | optical purity: ≥90% (HPLC, Marfey′s reagent) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | mouse ... Grin2a(14811)rat ... Grik1(29559), Grin2a(24409), Grin2b(24410), Grin2c(24411), Grin2d(24412) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D(−)-2-Amino-5-phosphonopentanoic acid used for?
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D(−)-2-Amino-5-phosphonopentanoic acid is primarily used as an NMDA receptor antagonist in neuroscience research, particularly for studying excitatory neurotransmission, cell signaling, and neurodegenerative processes.
What is the CAS number and chemical formula?
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The CAS number is 79055-68-8, and the empirical formula is C5H12NO5P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D(−)-2-Amino-5-phosphonopentanoic acid with an optical purity of ≥90% (HPLC, Marfey’s reagent). This product is supplied for research and laboratory use. Tech Serve Solutions does not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions?
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This compound is a Warning substance, indicated by GHS07. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Ensure good ventilation. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product is carefully packaged and exported according to international shipping regulations for chemical compounds.
How can I request a sample or a quote?
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Please contact our sales team through the website or by phone to request a sample or obtain a quotation for D(−)-2-Amino-5-phosphonopentanoic acid.
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