1-(4-Chlorobenzyl)piperazine
1-(4-Chlorobenzyl)piperazine (CAS 23145-88-2) is a halogenated piperazine building block with the molecular formula C11H15ClN2 and a molar mass of 210.70 g/mol. Tech Serve Solutions supplies it at 98% assay as a research-grade chemical for use in organic synthesis and medicinal chemistry. The compound combines a piperazine ring with a 4-chlorobenzyl substituent, making it a versatile intermediate for constructing more elaborate nitrogen heterocycles.
- Synonyms
- 1-(4-Chlorobenzyl)piperazine1-(4-Chlorobenzyl)-piperazine1-[(4-chlorophenyl)methyl]piperazine4-ChlorobenzylpiperazineN-(4-Chlorobenzyl)piperazinepara-Chlorobenzylpiperazine
Pharmaceutical and medicinal chemistry intermediate
Serves as a nitrogen-containing building block in the synthesis of pharmaceutical intermediates and candidate molecules. The piperazine ring is a common scaffold in medicinal chemistry, and the chlorobenzyl group provides a defined handle for further functionalisation.
Heterocyclic building block
Used to introduce a substituted piperazine moiety into target structures during multi-step organic synthesis. It is classified among halogenated heterocyclic building blocks and is valued for its reactivity at the secondary amine.
Research and laboratory reagent
Supplied as a research-grade reagent for laboratory-scale synthesis, method development and structure-activity studies. Its defined assay and physical constants support reproducible bench work.
Precursor for further derivatisation
The free secondary amine on the piperazine ring can be acylated, alkylated or otherwise derivatised, allowing the compound to act as a precursor to a range of more complex piperazine derivatives.
| Molecular weight | 210.70 |
|---|---|
| Empirical formula | C11H15ClN2 |
| Assay | 98% |
| Boiling point | 104-106 °C/0.1 mmHg(lit.) |
| Density | 1.140 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5580(lit.) |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Chlorobenzyl)piperazine used for?
+
It is used primarily as a building block and intermediate in organic and medicinal chemistry. The substituted piperazine ring is incorporated into larger molecules during multi-step synthesis, and the free secondary amine offers a convenient site for further derivatisation. It is supplied for research and manufacturing use rather than for any consumer application.
What is the CAS number and molecular formula of 1-(4-Chlorobenzyl)piperazine?
+
The CAS number is 23145-88-2 and the molecular formula is C11H15ClN2, with a molecular weight of 210.70 g/mol. The MDL number is MFCD00040791. Reported physical constants include a refractive index of n20/D 1.5580 and a density of 1.140 g/mL at 25 °C.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1-(4-Chlorobenzyl)piperazine at a typical assay of 98% as a technical/research-grade chemical. We do not represent this material as USP, BP or EP pharmacopoeia grade. A current specification or certificate of analysis can be provided with your enquiry to confirm the assay for your batch.
What are the safety and handling requirements for 1-(4-Chlorobenzyl)piperazine?
+
This is a hazardous corrosive material. It is classified under GHS05 and GHS07 with the signal word Danger, and carries hazard statements H302 (harmful if swallowed) and H314 (causes severe skin burns and eye damage). Handle it with gloves, goggles or a face shield and suitable respiratory protection, avoid contact with skin and eyes, and consult the Safety Data Sheet before use. It is also rated WGK 3 (highly hazardous to water in Germany).
How is 1-(4-Chlorobenzyl)piperazine packed, shipped and exported?
+
It is packed in appropriate corrosion-resistant containers sized to your order and shipped as a Class 8 corrosive substance under UN 2735, packing group III. As a global exporter, Tech Serve Solutions arranges compliant dangerous-goods documentation, labelling and packaging for international shipments. Available pack sizes and lead times are confirmed at the time of quotation.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with your required quantity, pack size and destination, and our team will respond with availability, specifications and a formal quotation. Samples can be discussed subject to availability and the applicable transport and regulatory requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis