D(−)-2-Amino-7-phosphonoheptanoic acid
D(−)-2-Amino-7-phosphonoheptanoic acid (CAS: 81338-23-0, C7H16NO5P) is a specialized chemical compound with a molecular weight of 225.18 g/mol. As a phosphono-analog of glutamate, it functions as a selective antagonist of the NMDA receptor. This property makes it a valuable tool in neuroscience research for studying excitatory amino acid pathways, ionotropic glutamate receptors, and neurotransmission.
- IUPAC
- D-AP-7
- Synonyms
- D-AP-7

Neuroscience Research
Utilised as a selective NMDA receptor antagonist to investigate glutamatergic neurotransmission and its role in neurological processes. It aids in studying ionotropic glutamate receptors and ligand-gated ion channels.
Cell Signaling Studies
Employed in cell biology to probe cellular signalling pathways, particularly those involving excitatory amino acids. Its action on NMDA receptors provides insights into neuronal excitability.
Pharmacological Tool
Serves as a research tool for developing and understanding drugs targeting NMDA receptors, crucial in neurological disorders research.
| Molecular weight | 225.18 |
|---|---|
| Empirical formula | C7H16NO5P |
| Form | solid |
| Colour | white |
| Solubility | H2O: soluble |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D(−)-2-Amino-7-phosphonoheptanoic acid used for?
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D(−)-2-Amino-7-phosphonoheptanoic acid is primarily used in neuroscience research as a selective NMDA receptor antagonist to study glutamatergic neurotransmission, ionotropic glutamate receptors, and cell signaling pathways.
What is the CAS number and molecular formula?
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The CAS number for D(−)-2-Amino-7-phosphonoheptanoic acid is 81338-23-0, and its molecular formula is C7H16NO5P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D(−)-2-Amino-7-phosphonoheptanoic acid as a white solid. The specific assay and purity are available on the product's Certificate of Analysis. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.
How should D(−)-2-Amino-7-phosphonoheptanoic acid be handled?
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Handle D(−)-2-Amino-7-phosphonoheptanoic acid with care. It is classified as a Warning substance and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use a dust mask type N95 (US), wear eyeshields and gloves. Ensure adequate ventilation, avoid breathing dust, and rinse eyes thoroughly if contact occurs. Refer to the Safety Data Sheet for detailed handling instructions.
How is D(−)-2-Amino-7-phosphonoheptanoic acid packed and shipped?
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D(−)-2-Amino-7-phosphonoheptanoic acid is carefully packed in appropriate containers for stable transport and is exported globally by Tech Serve Solutions in compliance with international shipping regulations.
How can I request a sample or quote?
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To request a sample or a quotation for D(−)-2-Amino-7-phosphonoheptanoic acid, please contact the Tech Serve Solutions sales team via the website or direct enquiry.
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