(S)-(−)-4-Hydroxy-2-pyrrolidinone
(S)-(−)-4-Hydroxy-2-pyrrolidinone (CAS: 68108-18-9, C4H7NO2) is a chiral heterocyclic compound with a molecular weight of 101.10 g/mol. This optically active lactam serves as a valuable building block in asymmetric synthesis and chemical manufacturing. Its specific stereochemistry makes it a key intermediate for creating complex chiral molecules, finding utility in research and development across various chemical sectors.
- IUPAC
- (S)-β-Hydroxy-γ-butyrolactam

Chiral Building Block
Utilised in organic synthesis to introduce specific stereochemistry into target molecules. Its defined chiral centre is critical for the stereoselective synthesis of complex pharmaceutical intermediates and fine chemicals.
Asymmetric Synthesis
Serves as a versatile precursor in asymmetric reactions, enabling the enantioselective construction of pyrrolidine derivatives and other chiral scaffolds.
Heterocyclic Chemistry
A key intermediate for the synthesis of various nitrogen-containing heterocyclic compounds. Its structure is amenable to further functionalization for diverse chemical applications.
| Molecular weight | 101.10 |
|---|---|
| Empirical formula | C4H7NO2 |
| Assay | 97% |
| Optical activity | [α]23/D −43°, c = 1 in ethanol |
| Melting point | 156-159 °C(lit.) |
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-4-Hydroxy-2-pyrrolidinone used for?
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(S)-(−)-4-Hydroxy-2-pyrrolidinone is primarily used as a chiral building block in asymmetric synthesis and for the preparation of various heterocyclic compounds in chemical research and development.
What are the CAS number and formula for (S)-(−)-4-Hydroxy-2-pyrrolidinone?
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The CAS number is 68108-18-9, and the empirical formula is C4H7NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-4-Hydroxy-2-pyrrolidinone with an assay of 97%. This product is supplied for research and manufacturing purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for this compound?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A respirator filter (type N95 or P1) is recommended. Users should follow P280 and P305 + P351 + P338 precautionary statements, which advise wearing protective clothing and rinsing eyes cautiously with water for several minutes.
Is (S)-(−)-4-Hydroxy-2-pyrrolidinone a controlled substance?
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The provided data does not indicate that (S)-(−)-4-Hydroxy-2-pyrrolidinone is a controlled substance.
How is (S)-(−)-4-Hydroxy-2-pyrrolidinone packed and shipped?
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Tech Serve Solutions securely packs and exports fine chemicals globally, adhering to all necessary regulations for safe transportation.
How can I request a sample or quote for (S)-(−)-4-Hydroxy-2-pyrrolidinone?
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To request a sample or a quote, please contact our sales department through the website or by calling us directly. Please provide the product name and CAS number for prompt service.
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