2-Chloro-3-methyl-5-nitropyridine
2-Chloro-3-methyl-5-nitropyridine (CAS: 22280-56-4), with the molecular formula C6H5ClN2O2 and a molecular weight of 172.57 g/mol, is a pyridine derivative. This compound serves as a valuable building block in organic synthesis, particularly within the realm of heterocyclic chemistry. It is frequently employed in the development of novel compounds and research chemicals, facilitating advancements in various scientific disciplines.
- IUPAC
- 2-Chloro-5-nitro-3-picoline

Organic Synthesis Intermediate
2-Chloro-3-methyl-5-nitropyridine is utilised as a key intermediate in multi-step organic synthesis pathways. Its functional groups allow for diverse chemical transformations.
Heterocyclic Chemistry
As a substituted pyridine, this compound is integral to the construction of complex heterocyclic structures. It is instrumental in research exploring new pyridine-based molecules.
Research and Development
This chemical finds application in research laboratories for the synthesis of novel compounds and the exploration of new chemical reactions. Its properties make it a useful reagent for scientific investigation.
| Molecular weight | 172.57 |
|---|---|
| Empirical formula | C6H5ClN2O2 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 45-50 °C |


Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-3-methyl-5-nitropyridine used for?
+
2-Chloro-3-methyl-5-nitropyridine is primarily used as a building block in organic synthesis and heterocyclic chemistry for research and development purposes.
What is the CAS number and chemical formula for 2-Chloro-3-methyl-5-nitropyridine?
+
The CAS number is 22280-56-4 and the chemical formula is C6H5ClN2O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Chloro-3-methyl-5-nitropyridine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Chloro-3-methyl-5-nitropyridine be handled safely?
+
2-Chloro-3-methyl-5-nitropyridine is a Danger hazard. It is toxic if swallowed, causes skin irritation, serious eye damage, and may cause respiratory irritation. Handle with appropriate personal protective equipment (gloves, eye protection, respiratory protection) in a well-ventilated area. Store at 2-8°C.
Is 2-Chloro-3-methyl-5-nitropyridine packed and shipped internationally?
+
Yes, Tech Serve Solutions is a global supplier and exporter and can pack and ship 2-Chloro-3-methyl-5-nitropyridine internationally, adhering to all relevant transport regulations (UN 2811, 6.1, PGIII).
How can I request a quote or sample for 2-Chloro-3-methyl-5-nitropyridine?
+
To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number (22280-56-4).
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis