Fotemustine
Fotemustine (CAS 92118-27-9) is a light yellow powder with the molecular formula C9H19ClN3O5P and a molecular weight of 315.69 g/mol. This compound is recognised for its role in cancer research, specifically in studies related to apoptosis and cell cycle regulation. It functions as a DNA intercalator and crosslinker, and is investigated as a potential therapeutic agent. Fotemustine is generally supplied for research purposes.
- IUPAC
- Mustophorane,(+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate,Muphoran,P-[1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-phosphonic acid diethyl ester,S 10036
- Synonyms
- Mustophorane(+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonateMuphoranP-[1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-phosphonic acid diethyl esterS 10036
Cancer Research Agent
Fotemustine is utilised in research settings to investigate its effects on cancer cells, focusing on mechanisms such as DNA damage and induction of programmed cell death (apoptosis). Its properties as a DNA crosslinker make it a subject of study for novel chemotherapeutic strategies.
Apoptosis and Cell Cycle Studies
The compound serves as a tool for researchers studying the intricate processes of apoptosis and the cell cycle. Its ability to interfere with DNA replication and repair pathways provides insights into cellular regulation and potential therapeutic targets.
Bioactive Small Molecule
As a bioactive small molecule, Fotemustine is employed in biochemical and pharmacological studies to understand its interactions with cellular components and its potential impact on biological systems. This includes its role in cell signaling pathways.
| Molecular weight | 315.69 |
|---|---|
| Empirical formula | C9H19ClN3O5P |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | light yellow |
| Solubility | H2O: ≥1 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | protect from light |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fotemustine used for?
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Fotemustine is primarily used in research settings for studies related to cancer, apoptosis, cell cycle regulation, and as a bioactive small molecule. It is investigated for its potential as a therapeutic agent due to its DNA crosslinking properties.
What are the CAS number and formula for Fotemustine?
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The CAS number for Fotemustine is 92118-27-9, and its molecular formula is C9H19ClN3O5P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fotemustine with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade; it is intended for research and laboratory use.
How should Fotemustine be handled and stored?
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Fotemustine is classified with hazard statement H351 (Suspected of causing cancer) and requires careful handling. It should be stored at 2-8°C, protected from light, and handled with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet for detailed guidance.
Is Fotemustine a controlled substance?
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The provided data does not indicate that Fotemustine is a controlled substance. However, regulations can vary by jurisdiction, and users should verify local compliance.
How is Fotemustine packed and shipped?
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Fotemustine is supplied as a light yellow powder and shipped according to standard chemical transport regulations. Specific packaging details can be provided upon request.
How can I request a quote or sample for Fotemustine?
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To request a quote or a sample of Fotemustine, please contact our sales team through the website or via email, providing your contact details and the quantity required.
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