(S)-(−)-4-Amino-2-hydroxybutyric acid
(S)-(−)-4-Amino-2-hydroxybutyric acid (CAS 40371-51-5), with the molecular formula H2NCH2CH2CH(OH)CO2H and a molecular weight of 119.12 g/mol, is a chiral building block. This optically active compound is primarily utilised in asymmetric synthesis as a key intermediate for the enantiopure synthesis of 3-hydroxypyrrolidin-2-ones. Its precise stereochemistry makes it valuable for creating complex chiral molecules in organic synthesis.
Chiral Building Block in Organic Synthesis
Serves as a crucial chiral synthon for the preparation of enantiomerically pure compounds. It is particularly important for constructing the 3-hydroxypyrrolidin-2-one scaffold.
Intermediate for Pharmaceutical Research
Its chiral nature and functional groups make it a valuable intermediate in the synthesis of complex molecules with potential pharmaceutical applications, facilitating stereoselective transformations.
Asymmetric Synthesis
Enables stereoselective synthesis routes, allowing chemists to precisely control the chirality of target molecules. This is vital for developing enantiopure drugs and fine chemicals.
| Molecular weight | 119.12 |
|---|---|
| Linear formula | H2NCH2CH2CH(OH)CO2H |
| Assay | 96% |
| Optical activity | [α]23/D −30°, c = 1 in H2O |
| Application | Building block for enantiopure 3-hydroxypyrrolidin-2-ones.1 |
| Melting point | 200-203 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-4-Amino-2-hydroxybutyric acid used for?
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(S)-(−)-4-Amino-2-hydroxybutyric acid is used as a building block for enantiopure 3-hydroxypyrrolidin-2-ones and in asymmetric synthesis.
What is the CAS number and formula for (S)-(−)-4-Amino-2-hydroxybutyric acid?
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The CAS number is 40371-51-5 and the linear formula is H2NCH2CH2CH(OH)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-4-Amino-2-hydroxybutyric acid with an assay of 96%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling considerations for this compound?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified with WGK 2 in Germany.
How is this chemical packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging and documentation for safe and compliant international shipment.
How can I request a sample or quote for (S)-(−)-4-Amino-2-hydroxybutyric acid?
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Please contact our sales team via the website to request a sample or a formal quotation for this product.
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