CZC-25146 hydrochloride
CZC-25146 hydrochloride (CAS: 1330003-04-7) is a chemical compound with the formula C22H25FN6O4S · HCl and a molecular weight of 525.00. This white to beige powder is primarily utilised in scientific research, particularly within cell biology and neuroscience. Its role in studying kinase/phosphatase pathways and protein kinases makes it a valuable reagent for investigating cell signalling mechanisms.
- IUPAC
- N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-methanesulfonamide hydrochloride

Cell Signalling Research
CZC-25146 hydrochloride serves as a tool in understanding complex cell signalling pathways. Its properties are investigated in the context of kinase and phosphatase biology, aiding researchers in dissecting cellular communication mechanisms.
Neuroscience Investigations
This compound finds application in neuroscience research, specifically in studies related to LRRK2 and protein kinases. It assists in exploring the roles of these proteins in neurological functions and related disorders.
Serine/Threonine Kinase Biology
As a selective inhibitor or modulator, CZC-25146 hydrochloride is employed in the study of serine/threonine kinase biology. Researchers use it to probe the functional significance of these enzymes in various biological processes.
| Molecular weight | 525.00 |
|---|---|
| Empirical formula | C22H25FN6O4S · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: >15 mg/mL (warmed) |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,Xi |
| Risk statements (R) | 25-36 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is CZC-25146 hydrochloride used for?
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CZC-25146 hydrochloride is used in scientific research, particularly in the fields of cell biology, cell signalling, neuroscience, and kinase/phosphatase biology, including studies involving LRRK2 and serine/threonine kinases.
What are the CAS number and chemical formula for CZC-25146 hydrochloride?
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The CAS number for CZC-25146 hydrochloride is 1330003-04-7, and its chemical formula is C22H25FN6O4S · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies CZC-25146 hydrochloride with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for CZC-25146 hydrochloride?
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CZC-25146 hydrochloride is classified with the GHS06 symbol and a 'Danger' signal word. It carries hazard statements H301 (Toxic if swallowed) and H319 (Causes serious eye irritation). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, should be used. Handle in a well-ventilated area. In case of accidental ingestion, seek immediate medical attention. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
How is CZC-25146 hydrochloride shipped and exported?
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CZC-25146 hydrochloride is shipped and exported according to relevant regulations for hazardous materials. The product is labelled with UN 2811, hazard class 6.1, and Packing Group III.
How can I request a sample or quote for CZC-25146 hydrochloride?
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To request a sample or a quote for CZC-25146 hydrochloride, please contact the Tech Serve Solutions sales team through our website or by phone. Provide the product name and CAS number for prompt service.
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